Invasive Lobular Carcinoma
| Classification according to ICD-10 | |
|---|---|
| C50 | Breast cancer |
| C50.0 | Nipple and areola |
| C50.1 | Central glandular body of the mammary gland |
| C50.2 | Upper inner quadrant of the mammary gland |
| C50.3 | Lower inner quadrant of the mammary gland |
| C50.4 | Upper outer quadrant of the mammary gland |
| C50.5 | Lower outer quadrant of the mammary gland |
| ICD-10 online (WHO version 2019) | |
An invasive lobular carcinoma ( English invasive lobular carcinoma or ILC ) is a malignant tumor whose origin is in the lobules of the mammary gland and which has invaded the surrounding tissue (invasive).
The classification, therapy and prognosis are as described under breast cancer .
Epidemiology
Depending on the source, the ILC accounts for around 10 to 20% of breast cancers.
Histology and morphology
The ILC often occurs bilaterally (both sides).
In this type of tumor, the spread of the carcinoma is mostly diffuse, which means that this carcinoma lacks a clear boundary. Often there is an arrangement of the tumor cells as a single file formation that can reach up to the nipple, or as an arrangement around the intralobular ductules (small milk ducts within the lobi) that looks like a target .
diagnosis
Due to the diffuse spread of invasive lobular carcinoma and the extremely rare formation of microcalcifications , the extent of the tumor spread within the mammary gland can almost only be determined with MRI and not with mammography .
