Janeway lesion

Janeway lesions are small erythematous or hemorrhagic spots or lumps on the palms of the hands or the soles of the feet.

As a secondary criterion of the Duke criteria, they indicate infectious (bacterial) endocarditis . The underlying germ is usually a staphylococcus . Their pathogenesis is likely due to bacterial microembolism.

The Janeway lesion is named after Theodore Caldwell Janeway (1872-1917). Janeway was a professor of internal medicine and worked primarily in the fields of cardiology and infectious diseases.

Osler nodules are very similar ; the difference is that these are tender and tend to lie on the end of the finger / toe.

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1. ↑ John Webster Kirklin , Brian G. Barratt-Boyes: Cardiac Surgery Morphology, diagnostic criteria, natural history, techniques, results and indications, Vol. 1 . 3rd ed. Churchill Livingstone Press, Philadelphia 2003, p. 694, ISBN 0-443-07526-3 .
2. ^ Charles A. Janeway: Presidential Address to The American Association of Immunologists. The road less traveled by; the role of innate immunity in the adaptive immune response . In: The Journal of Immunology , Vol. 161 (1998), No. 2, pp. 539-544, PMID 9670925 , ISSN  0022-1767 .
3. ↑ Farrior JB, Silverman ME: A consideration of the differences between a Janeway's lesion and to Osler's node in infectious endocarditis . In: Chest . 70, No. 2, August 1976, pp. 239-243. doi : 10.1378 / chest.70.2.239 . PMID 947688 .

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !