Lupus pernio

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Classification according to ICD-10
D86.3 Sarcoid of the skin
ICD-10 online (WHO version 2019)
Patient with lupus pernio.

The Lupus Pernio (from the Latin. Lupus = wolf and pernio = frostbite), also known as Lupus Pernio Besnier called, a relatively common manifestation is the großknotigen form of sarcoidosis . It describes an extensive, livid infiltration of the nose, cheeks and ear lobes. Internal organs can also be affected.

An epithelial cellular granuloma is found histologically . Live to pea-sized changes in the skin, mostly subcutaneous, under the pressure of a glass spatula you can see the dust-like, gray infiltrate nodules. There is apple jelly-like discoloration of the skin on pressure. In small-nodular sarcoid there are papular to pea-sized or small-nodular skin changes on the face, extremities, trunk and mucous membrane.

Diagnostics: The serum ACE concentration is increased in sarcoidosis and should be determined to monitor the progress.

Therapy: high spontaneous regression. Treatment is carried out with corticosteroids , chloroquine and PUVA , among others .

literature

  • Ingrid Moll: Dual Dermatology Series . Thieme Verlag, Stuttgart 2005, 6th edition ISBN 3-13-126686-4 .

Individual evidence

  1. ↑ M. Sand, D. Sand, C. Thrandorf, V. Paech, P. Altmeyer, FG Bechara: Cutaneous lesions of the nose. In: Head & face medicine Volume 6, 2010, p. 7, ISSN  1746-160X . doi : 10.1186 / 1746-160X-6-7 . PMID 20525327 . Open Access .

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