Medium acoustically evoked potentials
Medium AEPs (MAEP or AMLR (auditory middle latency response)) are a subgroup of the acoustic evoked potentials and were first identified in 1958 by Geisler et al. described. Their place of origin are the thalamic pathways and the primary auditory cortex. In contrast to the FAEP , not only the signal maxima (P as in “positive”) but also the minima (N as in “negative”) are evaluated: Wave Po, Na, Pa, Nb (transit time from 10 ms to 80 ms).
The areas of medical use in Europe are limited to the area of
- Neuromonitoring in anesthesia .
In the USA, the MAEPs have also been used since the 1990s for:
- frequency-specific hearing threshold estimates (e.g. in the case of aggravation )
- Diagnosis of thalamic disorders and AVWS
- Diagnosis of cortical stimulus filtering or habituation e.g. B. in schizophrenia , alcohol abuse; post-traumatic stress disorder (by the US Department of Veterans Affairs to soldiers with explosion trauma)
methodology
In contrast to the FAEP, the MAEP cannot be derived during sleep, in sedation with a reduction in amplitude. Hence the use for monitoring the depth of anesthesia. In children under 10 years of age, the potentials are only inconsistent. Leading points (10-20 system): C5 - A1 / A2 left hemisphere, C6 - A1 / A2 right hemisphere, Fz and Fn as the neutral electrode. It is stimulated with tone bursts , less often with clicks.
literature
James W. Hall: New Handbook of Auditory Evoked Potentials . Pearson, Boston MA 2006, ISBN 978-0-205-36104-5 .
Individual evidence
- ↑ CD Geisler, LS Frishkopf, WA Rosenblith: Extracranial responses to acoustic clicks in man. 1958, PMID 13592309
- ↑ M. Haensig, C. Philippi-Höhne, G. Hempel, U. Kaiser, U. Burkhardt: Impact of age using midlatency auditory evoked potentials during anesthesia with propofol and remifentanil in children. 2010
- ↑ clinicaltrials.gov