Mabinlin 1

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Mabinlin 1
other names

Mabinlin I, MAB I, Sweet protein mabinlin-1

Precursor 104 amino acids , 12,284 Da
Identifier
External IDs

Mabinlin 1 is a protein from the Chinese plant Capparis masaikai (Mabinlang) that creates a sweet taste on the tongue of people.

properties

Mabinlin 1, like its homologues Mabinlin 2 , Mabinlin 3 and Mabinlin 4 , is one of the Mabinlang 2S storage proteins. It has four disulfide bridges and is not thermally stable . After translation , it is post-translationally split into two parts by proteolysis , chain A (position 1-32) and chain B (position 33-104). It's about 10 times as sweet as sucrose for the same mass.

Homologues of Mabinlin 1

A chain
M-1: EPLCRRQFQQ HQHLRACQRY IRRRAQRGGL VD
M-2: QLWRCQRQFL QHQRLRACQR FIHRRAQFGG QPD
M-3: EPLCRRQFQQ HQHLRACQRY LRRRAQRGGL AD
M-4: EPLCRRQFQQ HQHLRACQRY LRRRAQRG

chain B
M-1: EQRGPALRLC CNQLRQVNKP CVCPVLRQAA HQQLYQGQIE GPRQVRQLFR AARNLPNICK IPAVGRCQFT RW
M-2 : QPRRPALRQC CNQLRQVDRP CVCPVLRQAA QQVLQRQIIQ GPQQLRRLFD AARNLPNICN IPNIGACPFR AW
M-3: EQRGPALRLC CNQLRQVNKP CVCPVLRQAA HQQLYQGQIE GPRQVRRLFR AARNLPNICK IPAVGRCQFT RW
M-4: EQRGPALRLC CNQLRQVNKP CVCPVLRQAA HQQLYQGQIE GPRQVRRLFR AARNLPNICK IPAVGRCQFT RW
amino acid sequences according to UniProt .

literature

  • S. Nirasawa, T. Nishino, M. Katahira, S. Uesugi, Z. Hu, Y. Kurihara: Structures of heat-stable and unstable homologues of the sweet protein mabinlin. The difference in the heat stability is due to replacement of a single amino acid residue. In: European Journal of Biochemistry . Volume 223, Number 3, August 1994, pp. 989-995, PMID 8055976 .
  • Y. Kurihara: Characteristics of antisweet substances, sweet proteins, and sweetness-inducing proteins. In: Critical reviews in food science and nutrition. Volume 32, Number 3, 1992, pp. 231-252, doi : 10.1080 / 10408399209527598 , PMID 1418601 .

Individual evidence

  1. ↑ a b c Sweet protein mabinlin-1 - Capparis masaikai (Mabinlang). In: uniprot.org. October 25, 2017, accessed October 23, 2018 .
  2. ↑ UniProtKB / Swiss-Prot P80351.
  3. ↑ UniProtKB / Swiss-Prot P30233.
  4. ↑ UniProtKB / Swiss-Prot P80352.
  5. ↑ UniProtKB / Swiss-Prot P80353.