Microsporidiosis
| Classification according to ICD-10 | |
|---|---|
| B60.8 | Microsporidiosis |
| ICD-10 online (WHO version 2019) | |
A microsporidiosis or microsporidiasis is a disease of various organisms (mammals, insects, crustaceans and numerous other groups) caused by microsporidia (obligate intracellular spore-forming fungi ). In humans, there is clinical relevance, particularly in the case of HIV infections.
The microsporidia include numerous genera, most of which only affect animals. Examples of clinical pictures of microsporidiosis are encephalitozoonosis , neon disease and nosemosis .
The diagnosis is carried out by means of a histological examination.
In human medicine, albendazole and fumagillin are used to treat microsporidiosis . Fumagillin, a substance obtained from Aspergillus fumigatus , is authorized in France (as of June 2010).
literature
- JA Shadduck, E. Greeley: Microsporidia and human infections . In: Clin Microbiol Rev . tape 2 , no. 2 , 1989, pp. 158-165 , PMID 2650860 , PMC 358108 (free full text).
- CJ Bacchi, LM Weiss, S. Lane, B. Frydman, A. Valasinas, V. Reddy et al .: Novel synthetic polyamines are effective in the treatment of experimental microsporidiosis, an opportunistic AIDS-associated infection . In: Antimicrob Agents Chemother . tape 46 , no. 1 , 2002, p. 55-61 , PMID 11751111 , PMC 127003 (free full text).
- Marianne Abele-Horn: Antimicrobial Therapy. Decision support for the treatment and prophylaxis of infectious diseases. With the collaboration of Werner Heinz, Hartwig Klinker, Johann Schurz and August Stich, 2nd, revised and expanded edition. Peter Wiehl, Marburg 2009, ISBN 978-3-927219-14-4 , p. 292 f.
