Murrough O'Brien
Murrough O'Brien is the name of the following people:
- Murrough O'Brien, 1st Earl of Inchiquin (1618–1674), Irish nobleman
- Murrough O'Brien, 1st Earl of Thomond († 1551), Irish nobleman, last King of Thomond
- Murrough O'Brien, 1st Marquess of Thomond (1726–1808), Irish-British nobleman and politician
- Murrough O'Brien, 3rd Baron Inchiquin (1550–1574), Irish nobleman
- Murrough O'Brien, 4th Baron Inchiquin (1563–1597), Irish nobleman