Neonatal Small Left Colon Syndrome

from Wikipedia, the free encyclopedia
Classification according to ICD-10
Q43.2 Other congenital dysfunction of the colon
ICD-10 online (WHO version 2019)

The Neonatal Small Left Colon Syndrome (NSLCS) is a childhood disease . It is a very rare functional disorder in newborns with an undersized colon in the descending thigh (descending colon) with an abrupt change in caliber at the level of the left bend ( flexura coli sinistra ). There is an association with maternal diabetes mellitus in about 50% .

The first description is from 1974 by WS Davis et al. He had found an increased number of immature ganglion cells .

root cause

The cause is not clear. To be discussed:

Clinical manifestations

Clinical criteria are:

Often they are children of diabetic mothers.

diagnosis

The diagnosis is based on clinical and radiological findings, especially the colonic enema .

Differential diagnostics

The following are to be excluded:

therapy

Usually the diagnostic enema is also therapeutic. The colon caliber usually returns to normal within a few weeks.

literature

  • ZL Kang, KG Revanna, AA Abdul Haium, B. Sriram: Neonatal small left colon syndrome. In: BMJ Case Reports. Volume 2015, October 2015, S., doi: 10.1136 / bcr-2015-211228 , PMID 26443091 , PMC 4600822 (free full text).
  • VS Amat, R. Núñez Núñez, E. Enríquez Zarabozo, C. Moreno Hurtado, E. Blesa Sánchez, RI Cavaco Fernandes: Síndrome del colon izquierdo pequeño: revisión de nuestra experiencia. In: Cirugia pediatrica: organo oficial de la Sociedad Espanola de Cirugia Pediatrica. Volume 24, Number 3, August 2011, pp. 156-160, PMID 22295657 .
  • A. Amrani, H. Zerhouni, MH Hachimi, F. Ettayebi, M. Benhammou: Le syndrome du “petit côlon gauche” (à propos de deux cas). In: Archives de pediatrie: organe officiel de la Societe francaise de pediatrie. Volume 9, Number 9, September 2002, pp. 917-920, PMID 12387173 .
  • R. Fotter: The "Neonatal small left colon syndrome" In: RöFo: Advances in the field of X-rays and nuclear medicine. Volume 134, Number 3, March 1981, pp. 324-326, doi: 10.1055 / s-2008-1056366 , PMID 6452390 .

Individual evidence

  1. ↑ a b emedicine
  2. ↑ a b A. Al-Salem: Small Left Colon Syndrome. In: An Illustrated Guide to Pediatric Surgery. Springer, Cham, 2014, doi : 10.1007 / 978-3-319-06665-3_29 , print ISBN 978-3-319-06664-6 , online ISBN 978-3-319-06665-3
  3. ^ H. Ellis, R. Kumar, B. Kostyrka: Neonatal small left colon syndrome in the offspring of diabetic mothers — an analysis of 105 children. In: Journal of Pediatric Surgery. 44, 2009, p. 2343, doi: 10.1016 / j.jpedsurg.2009.07.054 .
  4. ^ WS Davis, RP Allen, BE Favara, TL Slovis: Neonatal small left colon syndrome. In: The American journal of roentgenology, radium therapy, and nuclear medicine. Volume 120, Number 2, February 1974, pp. 322-329, PMID 4814217 .
  5. ^ DE Schofield, EJ Yunis: Intestinal neuronal dysplasia. In: Journal of Pediatric Gastroenterology and Nutrition . Volume 12, Number 2, February 1991, pp. 182-189, doi: 10.1097 / 00005176-199102000-00008 , PMID 2051270 .
  6. ↑ S. Maurin, K. Husseini, J. Gaudin, G. Levard: Small left colon syndrome in 3 sisters. In: Journal of pediatric surgery. [Electronic publication before printing] December 2014, doi: 10.1016 / j.jpedsurg.2012.07.038 , PMID 25783343 .
  7. ^ A b D. R. Stewart, GW Nixon, DG Johnson, VR Condon: Neonatal small left colon syndrome. In: Annals of surgery. Volume 186, number 6, December 1977, pp. 741-745, doi: 10.1097 / 00000658-197712000-00014 , PMID 603277 , PMC 1396513 (free full text).

Web links