Nucleic Acid Amplification Technology

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Nucleic Acid Amplification Technology ( NAAT ) in medicine stands for a group of processes in which nucleic acids are amplified so that even small amounts can be detected. The best known process is the polymerase chain reaction . Another method is Transcription Mediated Amplification (TMA). With this test procedure, the genetic material (DNA or RNA) of, for example, pathogens can be detected.

In the COVID-19 pandemic , the NAT test is used as the test for SARS-CoV-2 .

literature

  • SA Baylis, M. Chudy, CM Nübling: Standardization of NAT for Blood-Borne Pathogens. In: Transfusion medicine and hemotherapy: official organ of the German Society for Transfusion Medicine and Immunohamatology. Volume 42, number 4, July 2015, pp. 211-218, doi : 10.1159 / 000435872 , PMID 26557812 , PMC 4569255 (free full text).