Osteosclerosis
| Classification according to ICD-10 | |
|---|---|
| Q78.2 | Marble Bone Disease |
| M85.8 | Other specified changes in bone density and structure |
| ICD-10 online (WHO version 2019) | |
As osteosclerosis (synonym: Eburnisation , eburnation , from ancient Greek ὀστούν ostoun , German , bone ' and σκληρός skleros , German , hard' ), a sclerosis referred (hardening) of the bone tissue. This occurs as a local or generalized overgrowth ( hypertrophy ) of bone tissue, whereby the resilience is reduced.
Primary form
It occurs as a primary form (generalized) in osteopetrosis (marble bone disease), Engelmann syndrome , melorheostosis and other, rare syndromes, such as Lenz-Majewski syndrome , tricho-dento-osseous syndrome , trichothidystrophy type G or Raine Syndrome , also in infantile malignant osteopetrosis , in pycnodysostosis , osteopoikilosis ( Buschke-Ollendorff syndrome ) or together with leukocyte adhesion defects .
Further syndromes can be found under primary bone dysplasia with increased bone density .
Secondary form
Secondary forms are the consequences of other clinical pictures such as inflammation, tumors or kidney diseases.
An example is renal osteodystrophy , osteodystrophia deformans , osteomyelofibrosis , hypervitaminosis D , hypoparathyroidism or Schnitzler syndrome .
Osteosclerosis can also be caused by chronic, excessive fluoride intake. One then speaks of fluorosis . The pelvis, spine and ribs are mainly affected; pain can occur in the lower spine and sacrum.
Individual evidence
- ↑ Osteopetrosis, malignant, autosomal recessive form. In: Orphanet (Rare Disease Database).
- ↑ leukocyte adhesion defect. In: Orphanet (Rare Disease Database).
- ↑ Schnitzler syndrome. In: Orphanet (Rare Disease Database).
- ↑ Federal Association of Accident Insurance Funds: Information for first aid in the event of exposure to dangerous chemical substances, GUV-I 8504, 2007 ( page no longer available , search in web archives ) Info: The link was automatically marked as defective. Please check the link according to the instructions and then remove this notice. (PDF; 607 kB)
