Parallel reactor system
Parallel reactor systems are reaction vessels ( reactors ) operated via a joint control system in which chemical or biological processes take place. Parallel reactors are increasingly used primarily in chemical and pharmaceutical research and development.
In the field of biotechnological research, parallel bioreactor systems on a laboratory scale (ml to liter scale) are increasingly being used, which mostly consist of four, eight or 16 bioreactors .
The main advantages over individual (bio) reactors are time ( time-to-market ) and cost savings through small work volumes and simultaneous control. In addition, the reproducibility of the results should be guaranteed through complex software, automated control and extensive data acquisition and storage ( data mining ). The use of parallel reactor systems supports the analysis and control of processes according to industry standards such as Process Analytical Technology (PAT). In the statistical design of experiments (Engl. Design of Experiments ) in process development are increasingly being used parallel reactor systems.
Individual evidence
- ↑ Rachel Bareither and David Pollard: A Review of Advanced Small-Scale Parallel Bioreactor Technology for Accelerated Process Development. Current State and Future Need . In: Biotechnology Progress. A journal of food, pharmaceutical and bioengineering , vol. 27 (2011), issue 1, doi : 10.1002 / btpr.522 .