Pentraxins

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Pentraxins are either immune defense proteins or proteins that are homologous to them. A distinction is made between short and long pentraxins. Their function is very different. A common feature is a composition of 5 identical protomers , the short pentraxins are homologous to each other and to the C-terminal protein halves of the long pentraxins.

Short pentraxins

Long pentraxins

  • PTX3
  • Apexin
  • XL-PXN1 (XL = Xenopus laevis , a frog)
  • NPTX1 = neuronal pentraxin np1
  • NPTX2 = neuronal pentraxin np2 = NARP
  • NPR = neuronal pentraxin receptor

Individual evidence

  1. Jenny NS, et al .: Serum amyloid P and cardiovascular disease in older men and women: results from the Cardiovascular Health Study. Arterioscler Thromb Vasc Biol. 2007 Feb; 27 (2): pp. 352-358. Online , (PDF; 562 kB), PMID 17138933
  2. Linda B. Moran et al .: Neuronal pentraxin II is highly upregulated in Parkinson's disease and a novel component of Lewy bodies Acta Neuropathol. 2008 Apr; 115 (4): pp. 471-478; PMID 17987278 ; PMC 2270353 (free full text, PDF).