Scale-up
When scale-up is from the English ( to scale up , enlarge, expand) accepted term for the practice in chemical or biochemical process development scale-up of manufacturing processes. The aim is to build a technical production facility. The correct German designation “scale transfer” is rarely used today in favor of the English designation.
In the opposite case, if you z. If, for example, the malfunction of a large-scale plant is to be clarified through appropriate model tests, this is called scale-down .
application
In the case of scale-up, so-called dimensionless indicators such as B. the Reynolds number is determined, which are independent of the geometric dimensions. The key figures enable the design of the larger-scale production plant. Typical scale-up applications are the design of the stirrer drive or the temperature control system for a reactor .
A very recent new development that is supposed to simplify the scale-up is the mini-plant technology .
literature
- Marko Zlokarnik : Scale-up: Model transfer in process engineering . 2nd Edition. Wiley-VCH, 2005, ISBN 978-3527314225 .
- Maximilian Lackner: Scale-up in combustion. ProcessEng Engineering, 2009, ISBN 978-3902655042 .
- Alexandru Braha, Ghiocel Groza: Scale-up in wastewater technology. Wiley-VCH, 2006, ISBN 978-3527312702 .
Individual evidence
- ^ Siegfried Ebel and Hermann J. Roth (editors): Lexikon der Pharmazie , Georg Thieme Verlag, 1987, p. 583, ISBN 3-13-672201-9 .