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Senk is the family name of the following people:
- Andreas Senk (1960–1966), child, killed on the Berlin Wall
- Carl Ludwig Senk (1795–1846), German theater actor
- Dieter Senk (* 1957), German iron and steel engineer and university professor
- Herbert Senk (1900–1965), German art historian and playwright
- Karoline Antonie Senk (1791–1840), German theater actress
- Walter Senk (1927–2005), German journalist