Tolerance dose

In radiation therapy, the tolerance dose (dose tolerata) represents a dose that should not be exceeded for a tissue, organ or body , because otherwise irreparable damage is to be expected. Only deterministic radiation damage is taken into account here, and not stochastic late radiation effects .

The tolerance doses are defined in the relevant legal provisions or through recognized recommendations. In radiology , for example, the minimum and maximum tolerance dose is defined for organs at risk :

• The minimum tolerance dose , abbreviated to TD _5/5 , describes the dose which, under standard treatment conditions, does not cause complications of more than 5% within 5 years after treatment in a collective of patients.
• The maximum tolerance dose or TD _50/5 is accordingly the dose that leads to a maximum of 50% serious complications within 5 years.

The tolerance doses of the organs are in the order of about 15 Gy in 4 weeks in the eye and 40 Gy in 4 weeks in the spinal cord .

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• Eckhart Richter, Thomas Feyerabend: Basics of radiation therapy . 2nd edition, Springer Verlag, Berlin / Heidelberg, 2002. ISBN 978-3-540-41265-6 . Pp. 88-89.

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !