Trisomy 12
| Classification according to ICD-10 | |
|---|---|
| Q92.0 | Complete trisomy, meiotic nondisjunction |
| Q92.1 | Complete trisomy, mosaic (mitotic nondisjunction) |
| Q92.2 | Partial trisomy, major form
A whole arm or more doubled |
| Q92.3 | Partial trisomy, minor form
Less than a whole arm doubled |
| Q92.4 | Chromosome duplications that are only visible in the prometa phase |
| Q92.5 | Chromosome duplications, with other complex rearrangements |
| ICD-10 online (WHO version 2019) | |
The trisomy 12 is a (by the triple trisomic ) presence of genetic material of the 12th chromosome caused disability based on a genome mutation .
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- Free trisomy 12 : Type in which chromosome 12 is completely triple in all body cells.
- Translocation trisomy 12 : Type in which chromosome 12 is threefold in all body cells. However, one of the three chromosomes 12 or part of it has attached itself to a different chromosome. This "change of location" of a chromosome or a piece of chromosome is known as a translocation in genetics .
- Mosaic trisomy 12 : Type in which chromosome 12 is not present in triplicate in all body cells, but a cell line with the usual diploid set of chromosomes can be found at the same time. The presence of several karyotypes within an organism is called a mosaic in genetics .
- Partial trisomy 12 : Type in which a chromosome segment of one of the two chromosomes 12 is tripled. The chromosomes are indeed as usual twice before in all body cells, but one is part ( Part ) of the two chromosomes 12 verzweifacht, whereby one of the chromosomes is slightly longer than the other. The genetic information in this section is therefore available in three ways.
For other syndromes triggered by trisomy see there.
