Vasculogenesis

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Under the vasculogenesis (from latin vas , the vessel ' and Greek γένεση -genese , German , the birth' , 'Origin', Education ') is the formation of new blood vessels from endothelial progenitor cells which in bone marrow are formed. These are certain messenger substances ( cytokines ) - such as B. Vascular Endothelial Growth Factor (VEGF) - attracted and pass through the bloodstream to the point where the messenger substance is released, e.g. B. a wound , a tumor , the corpus luteum .

It is assumed that vasculogenesis plays a larger role in embryonic development ( embryogenesis ) and that angiogenesis plays the more important role in the adult organism .

literature

  • AM Joussen, B. Kirchhof, C. Gottstein: Molecular mechanisms of vasculogenesis and angiogenesis. In: The ophthalmologist. Volume 100, No. 4, 2003, pp. 284-291.