William Knox
William Knox is the name of the following people:
- William Knox (soccer player) , Scottish soccer player
- William Knox (1928–1999), Scottish writer and journalist, see Bill Knox
- William Knox D'Arcy (1849–1917), English lawyer and entrepreneur
- William F. Knox (1874–1944), American politician and publisher, see Frank Knox
- William Jess Knox , known as Willie Knox (born 1937), Scottish football player
- William Shadrach Knox (1843–1914), American lawyer and politician
- William W. Knox (1911–1981), American lawyer