Craig Mello
Craig Cameron Mello (born October 18, 1960 in New Haven , Connecticut ) is an American biochemist and Nobel laureate in physiology or medicine .
Life
Mello earned his Bachelor of Science degree in biochemistry from Brown University in 1982 and his PhD in Cell and Developmental Biology from Harvard University in 1990 . He then worked as a post-doctoral student at the Fred Hutchinson Cancer Research Center before moving to the Medical School of the University of Massachusetts in Worcester as Professor of Molecular Medicine in 1994 . He also holds the position of investigator at the Howard Hughes Medical Institute .
In 1998, he discovered together with Andrew Fire , the RNA interference to genes in eukaryotic cells off or to turn. It is an important method in biomedical research to study the function of individual genes. In addition, there have already been attempts to use RNA interference for therapeutic purposes.
Awards
- 2003: National Academy of Sciences Award in Molecular Biology
- 2003: Wiley Prize in Biomedical Sciences
- 2004: Massachusetts General Hospital Warren Triennial Prize , with Andrew Fire
- 2005: Gairdner Foundation International Award , together with Andrew Fire
- 2005: Dr. Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Science
- 2005: Massry Prize , together with Andrew Z. Fire
- 2005: Member of the US National Academy of Sciences
- 2006: Dr. Paul Janssen Award for Biomedical Research for the discovery of RNA interference and its biological functions
- 2006: Paul Ehrlich and Ludwig Darmstaedter Prize , together with Andrew Fire
- 2006: Nobel Prize in Physiology or Medicine , with Andrew Fire
- 2008: Member of the American Academy of Arts and Sciences
- 2009: Member of the American Philosophical Society
swell
- ↑ Andrew Fire, Siqun Xu, Mary K. Montgomery, Steven A. Kostas, Samuel E. Driver, Craig C. Mello: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans . In: Nature . Volume 391, 1998, pp. 806-811, PMID 9486653 doi : 10.1038 / 35888
literature
- Craig C. Mello , in: Internationales Biographisches Archiv 48/2006 of December 2, 2006, in the Munzinger archive ( beginning of article freely available)
Web links
- Craig Mello: Faculty in PMM - UMass Medical School Website by Craig Mello at the University of Massachusetts (English)
- Craig C. Mello Website of Craig Mello at the Howard Hughes Medical Institute (English)
- Information from the Nobel Foundation on the 2006 award to Craig Mello
| personal data | |
|---|---|
| SURNAME | Mello, Craig |
| ALTERNATIVE NAMES | Mello, Craig Cameron (full name) |
| BRIEF DESCRIPTION | American biochemist |
| DATE OF BIRTH | October 18, 1960 |
| PLACE OF BIRTH | New Haven , Connecticut |