ZFY: Difference between revisions

ZFY
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	1KLR, 1KLS, 1XRZ, 5ZNF
Identifiers
Aliases	ZFY, ZNF911, zinc finger protein, Y-linked, zinc finger protein Y-linked
External IDs	OMIM: 490000; HomoloGene: 88465; GeneCards: ZFY; OMA:ZFY - orthologs
Gene location (Human)
Chr.	Y chromosome (human)
End	2,982,506 bp
RNA expression pattern
	Top expressed in
	sperm; ; rectum; ; parietal pleura; ; trabecular bone; ; Achilles tendon; ; oral cavity; ; right lung; ; amniotic fluid; ; human penis; ; palpebral conjunctiva;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; metal ion binding; nucleic acid binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; nucleolus;
Biological process	multicellular organism development; transcription, DNA-templated; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7544
	n/a
	ENSG00000067646
	n/a
	P08048
	n/a
	NM_001145275; NM_001145276; NM_003411
	n/a
NP_001138747; NP_001138748; NP_003402; NP_001356631; NP_001356632;
	NP_001356633; NP_001356634; NP_001356635; NP_001356636; NP_001356637; NP_001356638; NP_001356639
	n/a
	Wikidata
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Revision as of 00:57, 4 June 2016

Zinc finger Y-chromosomal protein is a protein that in humans is encoded by the ZFY gene.^[3]^[4]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000067646 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Muller G, Schempp W (Jun 1989). "Mapping the human ZFX locus to Xp21.3 by in situ hybridization". Hum Genet. 82 (1): 82–4. doi:10.1007/BF00288279. PMID 2497060.
^ "Entrez Gene: ZFY zinc finger protein, Y-linked".

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 {{Infobox_gene}}
-'''Zinc finger Y-chromosomal protein''' is a [[protein]] that in humans is encoded by the ''ZFY'' [[gene]].<ref name="pmid2497060">{{cite journal | author = Muller G, Schempp W | title = Mapping the human ZFX locus to Xp21.3 by in situ hybridization | journal = Hum Genet | volume = 82 | issue = 1 | pages = 82–4 |date=Jun 1989 | pmid = 2497060 | pmc =  | doi =10.1007/BF00288279  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ZFY zinc finger protein, Y-linked| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7544| accessdate = }}</ref>
+'''Zinc finger Y-chromosomal protein''' is a [[protein]] that in humans is encoded by the ''ZFY'' [[gene]].<ref name="pmid2497060">{{cite journal | vauthors = Muller G, Schempp W | title = Mapping the human ZFX locus to Xp21.3 by in situ hybridization | journal = Hum Genet | volume = 82 | issue = 1 | pages = 82–4 |date=Jun 1989 | pmid = 2497060 | pmc =  | doi =10.1007/BF00288279  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ZFY zinc finger protein, Y-linked| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7544| accessdate = }}</ref>
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 | citations =
-*{{cite journal  | author=Merchant-Larios H, Moreno-Mendoza N |title=Onset of sex differentiation: dialog between genes and cells |journal=Arch. Med. Res. |volume=32 |issue= 6 |pages= 553–8 |year= 2002 |pmid= 11750730 |doi=10.1016/S0188-4409(01)00317-4  }}
+*{{cite journal  | vauthors=Merchant-Larios H, Moreno-Mendoza N |title=Onset of sex differentiation: dialog between genes and cells |journal=Arch. Med. Res. |volume=32 |issue= 6 |pages= 553–8 |year= 2002 |pmid= 11750730 |doi=10.1016/S0188-4409(01)00317-4  }}
 *{{cite journal   |vauthors=Kochoyan M, Havel TF, Nguyen DT, etal |title=Alternating zinc fingers in the human male associated protein ZFY: 2D NMR structure of an even finger and implications for "jumping-linker" DNA recognition |journal=Biochemistry |volume=30 |issue= 14 |pages= 3371–86 |year= 1991 |pmid= 1849423 |doi=10.1021/bi00228a004  }}
-*{{cite journal  | author=Kochoyan M, Keutmann HT, Weiss MA |title=Alternating zinc fingers in the human male associated protein ZFY: refinement of the NMR structure of an even finger by selective deuterium labeling and implications for DNA recognition |journal=Biochemistry |volume=30 |issue= 29 |pages= 7063–72 |year= 1991 |pmid= 1854720 |doi=10.1021/bi00243a005  }}
+*{{cite journal  | vauthors=Kochoyan M, Keutmann HT, Weiss MA |title=Alternating zinc fingers in the human male associated protein ZFY: refinement of the NMR structure of an even finger by selective deuterium labeling and implications for DNA recognition |journal=Biochemistry |volume=30 |issue= 29 |pages= 7063–72 |year= 1991 |pmid= 1854720 |doi=10.1021/bi00243a005  }}
 *{{cite journal   |vauthors=North M, Sargent C, O'Brien J, etal |title=Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY |journal=Nucleic Acids Res. |volume=19 |issue= 10 |pages= 2579–86 |year= 1991 |pmid= 2041734 |doi=10.1093/nar/19.10.2579  | pmc=328173  }}
 *{{cite journal   |vauthors=Palmer MS, Berta P, Sinclair AH, etal |title=Comparison of human ZFY and ZFX transcripts |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=87 |issue= 5 |pages= 1681–5 |year= 1990 |pmid= 2308929 |doi=10.1073/pnas.87.5.1681  | pmc=53546  }}
 *{{cite journal   |vauthors=Affara NA, Chambers D, O'Brien J, etal |title=Evidence for distinguishable transcripts of the putative testis determining gene (ZFY) and mapping of homologous cDNA sequences to chromosomes X,Y and 9 |journal=Nucleic Acids Res. |volume=17 |issue= 8 |pages= 2987–99 |year= 1989 |pmid= 2498838 |doi=10.1093/nar/17.8.2987  | pmc=317707  }}
-*{{cite journal  | author=Lau YF, Chan KM |title=The putative testis-determining factor and related genes are expressed as discrete-sized transcripts in adult gonadal and somatic tissues |journal=Am. J. Hum. Genet. |volume=45 |issue= 6 |pages= 942–52 |year= 1990 |pmid= 2511751 |doi=  | pmc=1683462  }}
+*{{cite journal  | vauthors=Lau YF, Chan KM |title=The putative testis-determining factor and related genes are expressed as discrete-sized transcripts in adult gonadal and somatic tissues |journal=Am. J. Hum. Genet. |volume=45 |issue= 6 |pages= 942–52 |year= 1990 |pmid= 2511751 |doi=  | pmc=1683462  }}
 *{{cite journal   |vauthors=Page DC, Mosher R, Simpson EM, etal |title=The sex-determining region of the human Y chromosome encodes a finger protein |journal=Cell |volume=51 |issue= 6 |pages= 1091–104 |year= 1988 |pmid= 3690661 |doi=10.1016/0092-8674(87)90595-2  }}
-*{{cite journal  | author=Tricoli JV, Bracken RB |title=ZFY gene expression and retention in human prostate adenocarcinoma |journal=Genes Chromosomes Cancer |volume=6 |issue= 2 |pages= 65–72 |year= 1993 |pmid= 7680890 |doi=10.1002/gcc.2870060202  }}
+*{{cite journal  | vauthors=Tricoli JV, Bracken RB |title=ZFY gene expression and retention in human prostate adenocarcinoma |journal=Genes Chromosomes Cancer |volume=6 |issue= 2 |pages= 65–72 |year= 1993 |pmid= 7680890 |doi=10.1002/gcc.2870060202  }}
-*{{cite journal  | author=Erlandsson R, Wilson JF, Pääbo S |title=Sex chromosomal transposable element accumulation and male-driven substitutional evolution in humans |journal=Mol. Biol. Evol. |volume=17 |issue= 5 |pages= 804–12 |year= 2000 |pmid= 10779541 |doi=  10.1093/oxfordjournals.molbev.a026359}}
+*{{cite journal  | vauthors=Erlandsson R, Wilson JF, Pääbo S |title=Sex chromosomal transposable element accumulation and male-driven substitutional evolution in humans |journal=Mol. Biol. Evol. |volume=17 |issue= 5 |pages= 804–12 |year= 2000 |pmid= 10779541 |doi=  10.1093/oxfordjournals.molbev.a026359}}
 *{{cite journal  | author=Mittwoch U |title=Three thousand years of questioning sex determination |journal=Cytogenet. Cell Genet. |volume=91 |issue= 1–4 |pages= 186–91 |year= 2001 |pmid= 11173854 |doi=10.1159/000056842  }}
 *{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
 *{{cite journal   |vauthors=Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, etal |title=The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes |journal=Nature |volume=423 |issue= 6942 |pages= 825–37 |year= 2003 |pmid= 12815422 |doi= 10.1038/nature01722 }}
-*{{cite journal  | author=Agate RJ, Choe M, Arnold AP |title=Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches |journal=Mol. Biol. Evol. |volume=21 |issue= 2 |pages= 384–96 |year= 2004 |pmid= 14660691 |doi= 10.1093/molbev/msh027 }}
+*{{cite journal  | vauthors=Agate RJ, Choe M, Arnold AP |title=Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches |journal=Mol. Biol. Evol. |volume=21 |issue= 2 |pages= 384–96 |year= 2004 |pmid= 14660691 |doi= 10.1093/molbev/msh027 }}
 *{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
 }}
 {{refend}}
 {{PDB Gallery|geneid=7544}}
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 [[Category:Genes on human chromosome Y]]
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Revision as of 00:57, 4 June 2016

References

Further reading