Babesia microti: Difference between revisions
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[[Image:Babesia life cycle human en.svg|thumb|360px|Life cycle of T. microti, including human infection]] |
[[Image:Babesia life cycle human en.svg|thumb|360px|Life cycle of T. microti, including human infection]] |
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'''Theileria microti''' is a parasitic blood-borne [[piroplasm]] transmitted by [[Ixodes scapularis|deer tick]]s. It was previously in the [[taxonomy|taxonomic]] [[genus]] ''[[Babesia]]'', as ''Babesia microti'', until [[ribosomal RNA]] comparisons placed it in the sister genus ''[[Theileria]]''.<ref>{{cite journal |author=UILENBERG,G. & GOFF,W.L. |title=Polyphasic Taxonomy |journal=Annals of the New York Academy of Sciences |volume=1081|pages=495 |year=2006 |doi=10.1196/annals.1373.073 |pmid=17135557}}[http://www.blackwell-synergy.com/doi/pdf/10.1196/annals.1373.073] </ref><ref> {{cite journal | doi = 10.1016/j.vetpar.2006.01.035 | year = 2006 | month = May | author = Uilenberg, G | title = Babesia--a historical overview | volume = 138 | issue = 1-2 | pages = 3–10 | pmid = 16513280 | journal = Veterinary |
'''Theileria microti''' is a parasitic blood-borne [[piroplasm]] transmitted by [[Ixodes scapularis|deer tick]]s. It was previously in the [[taxonomy|taxonomic]] [[genus]] ''[[Babesia]]'', as ''Babesia microti'', until [[ribosomal RNA]] comparisons placed it in the sister genus ''[[Theileria]]''.<ref>{{cite journal |author=UILENBERG,G. & GOFF,W.L. |title=Polyphasic Taxonomy |journal=[[Annals of the New York Academy of Sciences]] |volume=1081|pages=495 |year=2006 |doi=10.1196/annals.1373.073 |pmid=17135557}}[http://www.blackwell-synergy.com/doi/pdf/10.1196/annals.1373.073] </ref><ref> {{cite journal | doi = 10.1016/j.vetpar.2006.01.035 | year = 2006 | month = May | author = Uilenberg, G | title = Babesia--a historical overview | volume = 138 | issue = 1-2 | pages = 3–10 | pmid = 16513280 | journal = [[Veterinary Parasitology (journal)|Veterinary Parasitology]] }}</ref> ''T. microti'' is responsible for the disease [[human theileriosis]], similar to [[babesiosis]], a [[malaria]]-like disease which also causes fever and [[hemolysis]]. |
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An important difference from malaria is that ''T. microti'' does not infect liver cells. Additionally, the piroplasm is spread by tick bites (''[[Ixodes scapularis]]'', the same tick that spreads [[Lyme disease]]), while the malaria protozoans are spread via mosquito. Finally, under the microscope, the merozoite form of the ''T. microti'' lifecycle in red blood cells forms a cross-shaped structure, often referred to as a "[[Maltese cross]]", whereas malaria forms more of a diamond ring structure in red blood cells.<ref>{{cite book|last=Goldberg|first=Stephen |title=Clinical Microbiology made Ridiculously Simple|edition=4th |date=2007 |publisher=Medmaster|isbn=978-0940780217}}</ref> |
An important difference from malaria is that ''T. microti'' does not infect liver cells. Additionally, the piroplasm is spread by tick bites (''[[Ixodes scapularis]]'', the same tick that spreads [[Lyme disease]]), while the malaria protozoans are spread via mosquito. Finally, under the microscope, the merozoite form of the ''T. microti'' lifecycle in red blood cells forms a cross-shaped structure, often referred to as a "[[Maltese cross]]", whereas malaria forms more of a diamond ring structure in red blood cells.<ref>{{cite book|last=Goldberg|first=Stephen |title=Clinical Microbiology made Ridiculously Simple|edition=4th |date=2007 |publisher=Medmaster|isbn=978-0940780217}}</ref> |
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==External links== |
==External links== |
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* [http://www.health.state.mn.us/divs/idepc/diseases/babesiosis/index.html Minnesota Department of Health] |
* [http://www.health.state.mn.us/divs/idepc/diseases/babesiosis/index.html Minnesota Department of Health] |
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{{parasite-stub}} |
{{parasite-stub}} |
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[[Category: Parasites]] |
[[Category: Parasites]] |
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Revision as of 11:12, 25 September 2009
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Theileria microti is a parasitic blood-borne piroplasm transmitted by deer ticks. It was previously in the taxonomic genus Babesia, as Babesia microti, until ribosomal RNA comparisons placed it in the sister genus Theileria.[1][2] T. microti is responsible for the disease human theileriosis, similar to babesiosis, a malaria-like disease which also causes fever and hemolysis.
An important difference from malaria is that T. microti does not infect liver cells. Additionally, the piroplasm is spread by tick bites (Ixodes scapularis, the same tick that spreads Lyme disease), while the malaria protozoans are spread via mosquito. Finally, under the microscope, the merozoite form of the T. microti lifecycle in red blood cells forms a cross-shaped structure, often referred to as a "Maltese cross", whereas malaria forms more of a diamond ring structure in red blood cells.[3]
References
- ^ UILENBERG,G. & GOFF,W.L. (2006). "Polyphasic Taxonomy". Annals of the New York Academy of Sciences. 1081: 495. doi:10.1196/annals.1373.073. PMID 17135557.
{{cite journal}}: CS1 maint: multiple names: authors list (link)[1] - ^ Uilenberg, G (2006). "Babesia--a historical overview". Veterinary Parasitology. 138 (1–2): 3–10. doi:10.1016/j.vetpar.2006.01.035. PMID 16513280.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Goldberg, Stephen (2007). Clinical Microbiology made Ridiculously Simple (4th ed.). Medmaster. ISBN 978-0940780217.
External links
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