Boswellia serrata: Difference between revisions

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</ref><ref>https://americanindianimports.com/content/9_shallaki-natural-anti-inflammatory</ref>
</ref><ref>https://americanindianimports.com/content/9_shallaki-natural-anti-inflammatory</ref>
[[Image:Boswellia serrata (Salai) in Kinnarsani WS, AP W IMG_5843.jpg|thumb|250px|left|in [[Kinnerasani Wildlife Sanctuary]], [[Andhra Pradesh]], [[India]]. ]]
[[Image:Boswellia serrata (Salai) in Kinnarsani WS, AP W IMG_5843.jpg|thumb|250px|left|in [[Kinnerasani Wildlife Sanctuary]], [[Andhra Pradesh]], [[India]]. ]]
Extracts of ''Boswellia serrata'' have been clinically studied for [[osteoarthritis]] and joint function, particularly for osteoarthritis of the knee, with the research showing a slight improvement of both pain and function compared to a placebo.<ref>{{cite web |first1=M |last1=Cameron |first2=S |last2=Chrubasik |title=Oral herbal therapies for treating osteoarthritis |publisher=Cochrane Summaries |date=May 22, 2014 |url=http://summaries.cochrane.org/CD002947/oral-herbal-therapies-for-treating-osteoarthritis |accessdate=June 6, 2014}}</ref> Positive effects of Boswellia in some chronic inflammatory diseases including rheumatoid arthritis, bronchial asthma, osteoarthritis, ulcerative colitis and Crohn's disease have been reported.<ref>{{cite journal | last1 = Ammon | first1 = HP | year = 2010 | title = Modulation of the immune system by Boswellia serrata extracts and boswellic acids | url = | journal = Phytomedicine | volume = 17 | issue = 11| pages = 862–7 | doi=10.1016/j.phymed.2010.03.003}}</ref> A ''Boswellia'' extract marketed under the name Wokvel has undergone human efficacy, comparative, pharmacokinetic studies.<ref>Open, randomized, controlled clinical trial of Boswellia serrata extract as compared to valdecoxib in osteoarthritis of knee" ''Indian Journal of Pharmacology'' 2007; 39(1) 27-29</ref><ref>{{cite journal | date = Jan 2003 | title = Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial | url = | journal = Phytomedicine | volume = 10 | issue = 1| pages = 3–7 | doi=10.1078/094471103321648593}}</ref><ref>{{cite journal | date = Feb 2004 | title = Pharmacokinetic study of 11-Keto beta-Boswellic acid | url = | journal = Phytomedicine | volume = 11 | issue = 2-3| pages = 255–60 | doi=10.1078/0944-7113-00290}}</ref> Some see Boswellia serrata as a promising alternative to [[NSAIDs]], warranting further investigation in pharmacological studies and clinical trials.<ref>{{cite journal | last1 = Abdel-Tawab | first1 = M | last2 = Werz | first2 = O | last3 = Schubert-Zsilavecz | first3 = M | date = Jun 2011 | title = Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data | url = | journal = Clin Pharmacokinet | volume = 50 | issue = 6| pages = 349–69 | doi=10.2165/11586800-000000000-00000 | pmid=21553931}}</ref><ref>{{cite journal | pmc = 3309643 | pmid=22457547 | doi=10.4103/0250-474X.93507 | volume=73 | title=Boswellia serrata, a potential antiinflammatory agent: an overview | year=2011 | journal=Indian J Pharm Sci | pages=255–61 | last1 = Siddiqui | first1 = MZ}}</ref>
Extracts of ''Boswellia serrata'' have been clinically studied for [[osteoarthritis]] and joint function, particularly for osteoarthritis of the knee, with the research showing a slight improvement of both pain and function compared to a placebo.<ref>{{cite web |first1=M |last1=Cameron |first2=S |last2=Chrubasik |title=Oral herbal therapies for treating osteoarthritis |publisher=Cochrane Summaries |date=May 22, 2014 |url=http://summaries.cochrane.org/CD002947/oral-herbal-therapies-for-treating-osteoarthritis |accessdate=June 6, 2014}}</ref> Positive effects of Boswellia in some chronic inflammatory diseases including rheumatoid arthritis, bronchial asthma, osteoarthritis, ulcerative colitis and Crohn's disease have been reported.<ref>{{cite journal | last1 = Ammon | first1 = HP | year = 2010 | title = Modulation of the immune system by Boswellia serrata extracts and boswellic acids | url = | journal = Phytomedicine | volume = 17 | issue = 11| pages = 862–7 | doi=10.1016/j.phymed.2010.03.003}}</ref> Some see Boswellia serrata as a promising alternative to [[NSAIDs]], warranting further investigation in pharmacological studies and clinical trials.<ref>{{cite journal | last1 = Abdel-Tawab | first1 = M | last2 = Werz | first2 = O | last3 = Schubert-Zsilavecz | first3 = M | date = Jun 2011 | title = Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data | url = | journal = Clin Pharmacokinet | volume = 50 | issue = 6| pages = 349–69 | doi=10.2165/11586800-000000000-00000 | pmid=21553931}}</ref><ref>{{cite journal | pmc = 3309643 | pmid=22457547 | doi=10.4103/0250-474X.93507 | volume=73 | title=Boswellia serrata, a potential antiinflammatory agent: an overview | year=2011 | journal=Indian J Pharm Sci | pages=255–61 | last1 = Siddiqui | first1 = MZ}}</ref>


=== Topical application===
=== Topical application===

Revision as of 06:22, 28 July 2016

Boswellia serrata
in Kinnerasani Wildlife Sanctuary, Andhra Pradesh, India.
Scientific classification
Kingdom:
Plantae
(unranked):
Angiosperms
(unranked):
Eudicots
(unranked):
Rosids
Order:
Sapindales
Family:
Burseraceae
Genus:
Boswellia
Species:
B. serrata
Binomial name
Boswellia serrata

Boswellia serrata is a plant that produces Indian frankincense, Salai, referred to in Sanskrit as shallaki and in Latin as Olibanum Indicum.[1] the plant is native to much of India and the Punjab region that extends into Pakistan.[2]

Medical usage

In Ayurvedic medicine Indian frankincense has been used for hundreds of years for the treatment of arthritis.[3][4]

in Kinnerasani Wildlife Sanctuary, Andhra Pradesh, India.

Extracts of Boswellia serrata have been clinically studied for osteoarthritis and joint function, particularly for osteoarthritis of the knee, with the research showing a slight improvement of both pain and function compared to a placebo.[5] Positive effects of Boswellia in some chronic inflammatory diseases including rheumatoid arthritis, bronchial asthma, osteoarthritis, ulcerative colitis and Crohn's disease have been reported.[6] Some see Boswellia serrata as a promising alternative to NSAIDs, warranting further investigation in pharmacological studies and clinical trials.[7][8]

Topical application

Boswellia serrata has been recently developed for topical use in a patent-pending formula in Sano Relief Gel. Boswellia serrata is used in the manufacture of the anti-wrinkle agent "Boswelox",[9] which has been criticised as being ineffective.[10]

Active constituents

Boswellic acid and other pentacyclic triterpene acids are present. Beta-boswellic acid is the major constituent.

Mechanism of action

Animal studies performed in India show ingestion of a defatted alcoholic extract of Boswellia decreased polymorphonuclear leukocyte infiltration and migration, decreased primary antibody synthesis and almost totally inhibited the classical complement pathway.[11][12]

Properties

Shallaki has potent analgesic and anti-inflammatory effects that can reduce the pain and inflammation of joints.[13]

External links

  • BBC News Health - Frankincense 'can ease arthritis' Friday 01/08/08
  • "Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data". Clin Pharmacokinet. 50: 349–69. Jun 2011. doi:10.2165/11586800-000000000-00000. PMID 21553931. [14]

References

  1. ^ European Scientific Cooperative on Phytotherapy (2009). E/S/C/O/P Monographs: The Scientific Foundation for Herbal Medicinal Products. Second Edition, Supplement 2009. European Scientific Cooperative on Phytotherapy. p. 184. ISBN 9781901964080.
  2. ^ "USDA GRIN Taxonomy". Retrieved 15 October 2014.
  3. ^ "JOINT RELIEF". www.herbcompanion.com. Retrieved 2009-01-12.
  4. ^ https://americanindianimports.com/content/9_shallaki-natural-anti-inflammatory
  5. ^ Cameron, M; Chrubasik, S (May 22, 2014). "Oral herbal therapies for treating osteoarthritis". Cochrane Summaries. Retrieved June 6, 2014.
  6. ^ Ammon, HP (2010). "Modulation of the immune system by Boswellia serrata extracts and boswellic acids". Phytomedicine. 17 (11): 862–7. doi:10.1016/j.phymed.2010.03.003.
  7. ^ Abdel-Tawab, M; Werz, O; Schubert-Zsilavecz, M (Jun 2011). "Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data". Clin Pharmacokinet. 50 (6): 349–69. doi:10.2165/11586800-000000000-00000. PMID 21553931.
  8. ^ Siddiqui, MZ (2011). "Boswellia serrata, a potential antiinflammatory agent: an overview". Indian J Pharm Sci. 73: 255–61. doi:10.4103/0250-474X.93507. PMC 3309643. PMID 22457547.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  9. ^ Wrinkle breakthrough claim from L'Oreal
  10. ^ L'Oreal slammed over cream claims
  11. ^ Sharma, ML; Khajuria, A; Kaul, A; et al. (1988). "Effects of salai guggal ex-Boswellia serrata on cellular and humoral immune responses and leukocyte migration". Agents Actions. 24: 161–164. doi:10.1007/bf01968095.
  12. ^ Sharma, ML; Bani, S; Singh, GB (1989). "Anti-arthriticactivity of boswellic acids in bovine serum albumin (BSA)-induced arthritis". Int J Immunopharmacol. 11: 647–652. doi:10.1016/0192-0561(89)90150-1.
  13. ^ (Planta Med. 1971 Apr; 19(4): 333-41 for analgesic and psychopharmacological effects of gum resin of Boswalia Serrata by Memon MK)
  14. ^ Abdel-Tawab, M; Werz, O; Schubert-Zsilavecz, M (Jun 2011). "Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data". Clin Pharmacokinet. 50 (6): 349–69. doi:10.2165/11586800-000000000-00000. PMID 21553931.
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