Boswellia serrata: Difference between revisions
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David notMD (talk | contribs) →Mechanism of action: animal research from 1980s not sufficient to support a mechanism theory |
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=== Active constituents === |
=== Active constituents === |
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[[Boswellic acid]] and other pentacyclic [[triterpene]] acids are present. Beta-boswellic acid is the major constituent. |
[[Boswellic acid]] and other pentacyclic [[triterpene]] acids are present. Beta-boswellic acid is the major constituent. |
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=== Mechanism of action === |
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Animal studies performed in India show ingestion of a defatted alcoholic extract of ''Boswellia'' decreased polymorphonuclear leukocyte infiltration and migration, decreased primary antibody synthesis and almost totally inhibited the classical complement pathway.<ref>{{cite journal | last1 = Sharma | first1 = ML | last2 = Khajuria | first2 = A | last3 = Kaul | first3 = A | display-authors = etal | year = 1988 | title = Effects of salai guggal ex-Boswellia serrata on cellular and humoral immune responses and leukocyte migration | url = | journal = Agents Actions | volume = 24 | issue = | pages = 161–164 | doi=10.1007/bf01968095}}</ref><ref>{{cite journal | last1 = Sharma | first1 = ML | last2 = Bani | first2 = S | last3 = Singh | first3 = GB | year = 1989 | title = Anti-arthriticactivity of boswellic acids in bovine serum albumin (BSA)-induced arthritis | url = | journal = Int J Immunopharmacol | volume = 11 | issue = | pages = 647–652 | doi=10.1016/0192-0561(89)90150-1}}</ref> |
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==External links== |
==External links== |
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Revision as of 02:45, 22 March 2017
| Boswellia serrata | |
|---|---|
_in_Kinnarsani_WS,_AP_W2_IMG_5840.jpg)
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| in Kinnerasani Wildlife Sanctuary, Andhra Pradesh, India. | |
| Scientific classification | |
| Kingdom: | |
| (unranked): | |
| (unranked): | |
| (unranked): | |
| Order: | |
| Family: | |
| Genus: | |
| Species: | B. serrata
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| Binomial name | |
| Boswellia serrata | |
Boswellia serrata is a plant that produces Indian frankincense, Salai, referred to in Sanskrit as shallaki and in Latin as Olibanum Indicum.[1] the plant is native to much of India and the Punjab region that extends into Pakistan.[2]
Medical usage
In Ayurvedic medicine Indian frankincense has been used for hundreds of years for the treatment of arthritis.[3][4]
_in_Kinnarsani_WS,_AP_W_IMG_5843.jpg)
Extracts of Boswellia serrata have been clinically studied for osteoarthritis and joint function, particularly for osteoarthritis of the knee, with the research showing a slight improvement of both pain and function compared to a placebo.[5] Positive effects of Boswellia in some chronic inflammatory diseases including rheumatoid arthritis, bronchial asthma, osteoarthritis, ulcerative colitis and Crohn's disease have been reported.[6] Some see Boswellia serrata as a promising alternative to NSAIDs, warranting further investigation in pharmacological studies and clinical trials.[7][8]
Topical application
Boswellia serrata has been recently developed for topical use in a patent-pending formula in Sano Relief Gel. Boswellia serrata is used in the manufacture of the anti-wrinkle agent "Boswelox",[9] which has been criticised as being ineffective.[10]
Active constituents
Boswellic acid and other pentacyclic triterpene acids are present. Beta-boswellic acid is the major constituent.
External links
- BBC News Health - Frankincense 'can ease arthritis' Friday 01/08/08
References
- ^ European Scientific Cooperative on Phytotherapy (2009). E/S/C/O/P Monographs: The Scientific Foundation for Herbal Medicinal Products. Second Edition, Supplement 2009. European Scientific Cooperative on Phytotherapy. p. 184. ISBN 9781901964080.
- ^ "USDA GRIN Taxonomy". Retrieved 15 October 2014.
- ^ "JOINT RELIEF". www.herbcompanion.com. Retrieved 2009-01-12.
- ^ https://americanindianimports.com/content/9_shallaki-natural-anti-inflammatory
- ^ Cameron, M; Chrubasik, S (May 22, 2014). "Oral herbal therapies for treating osteoarthritis". Cochrane Summaries. Retrieved June 6, 2014.
- ^ Ammon, HP (2010). "Modulation of the immune system by Boswellia serrata extracts and boswellic acids". Phytomedicine. 17 (11): 862–7. doi:10.1016/j.phymed.2010.03.003.
- ^ Abdel-Tawab, M; Werz, O; Schubert-Zsilavecz, M (Jun 2011). "Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data". Clin Pharmacokinet. 50 (6): 349–69. doi:10.2165/11586800-000000000-00000. PMID 21553931.
- ^ Siddiqui, MZ (2011). "Boswellia serrata, a potential antiinflammatory agent: an overview". Indian J Pharm Sci. 73: 255–61. doi:10.4103/0250-474X.93507. PMC 3309643. PMID 22457547.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ Wrinkle breakthrough claim from L'Oreal
- ^ L'Oreal slammed over cream claims