Ravindra Gupta

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Ravindra Gupta
EducationBMBCh Oxford University
MPH Harvard School of Public Health
MA Cambridge University
PhD University College London
Scientific career
InstitutionsUniversity of Cambridge
University College London

Professor Ravindra "Ravi" Kumar Gupta is a professor of clinical microbiology at the Cambridge Institute of Therapeutic Immunology and Infectious Disease at the University of Cambridge. He is also a member of the faculty of the Africa Health Research Institute in Durban, South Africa.

Gupta was included in Time Magazine's 100 Most Influential People in 2020.[1]

Education

Gupta attended Brentwood School from 1987 to 1994. Gupta gained his undergraduate medical degree from Cambridge University in 1997 and then clinical degree from Oxford University in 2001, whilst completing a Master in Public Health at Harvard School of Public Health (1998-1999). He subsequently trained in infectious diseases in Oxford and The Hospital for Tropical Diseases (UCLH) and completed a PhD in Virology with Deenan Pillay and Greg Towers at UCL.

Biography

Gupta is married with three children.

Career

Gupta researches HIV, from basic science of how the virus interacts with human cells and the immune system to the emerging problem of drug resistant HIV. More recently he has worked on COVID-19 rapid diagnostics, SARS-CoV-2 intra host evolution and innate immunity.

Gupta was formerly Full Professor at University College London (2016-2019) [2][3] He is head of the Gupta Lab and has been a Wellcome Trust Fellowship holder since 2007.[4]

Gupta's work spans the UK and sub Saharan Africa. The lab focuses on two areas:

  • HIV drug resistance and implications for global scale up of antiretroviral therapy.[5]
  • Dissecting the biology of macrophage-virus interactions given myeloid cells are parasitised by HIV and are a difficult-to-treat reservoir.[6]

In March 2019 it was reported that Gupta led a team demonstrating HIV remission in a HIV positive man with advanced Hodgkin's lymphoma following an 'unrelated' stem cell transplant, the so-called London Patient.[7][8][9] After a bone marrow transplant from an HIV-resistant donor, the London Patient remained "functionally cured"[10] of his HIV. This is the second case of a patient cured of HIV. The first patient is referred to as the Berlin Patient.

References

  1. ^ "Ravindra Gupta: The 100 Most Influential People of 2020". Time. Retrieved 2020-09-23.
  2. ^ "Professor Ravindra Gupta". Ucl.ac.uk. 28 June 2018. Retrieved 5 March 2019.
  3. ^ "Ravi Gupta". Ahri.org. Retrieved 5 March 2019.
  4. ^ "UCL - London's Global University". Ucl.ac.uk. Retrieved 5 March 2019.
  5. ^ "Ravindra Gupta - CITIID". Cambridge Institute of Therapeutic Immunology & Infectious Disease. Retrieved 2020-09-23.
  6. ^ "Ravindra Gupta - CITIID". Cambridge Institute of Therapeutic Immunology & Infectious Disease. Retrieved 2020-09-23.
  7. ^ "UK man 'free' of HIV with new stem cells". Bbc.co.uk. 5 March 2019. Retrieved 5 March 2019.
  8. ^ "London patient becomes second adult to be cleared of HIV". Theguardian.com. 5 March 2019. Retrieved 5 March 2019.
  9. ^ Apoorva Mandavilli (4 March 2019). "H.I.V. Is Reported Cured in a Second Patient, a Milestone in the Global AIDS Epidemic". Nytimes.com. Retrieved 5 March 2019.
  10. ^ Kelland, Kate (2020-07-03). "'Don't give up hope' in fighting viruses, says 'cured' London AIDS patient". Reuters. Retrieved 2020-09-23.