Cloprostenol

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Cloprostenol
Clinical data
Trade namesCyclomate, Estrumate
Routes of
administration
Intramuscular
Pharmacokinetic data
Excretion67% renal, 25% fecal
Identifiers
  • (5Z)-7-{(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl}-5-heptenoic acid
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
ECHA InfoCard100.050.009 Edit this at Wikidata
Chemical and physical data
FormulaC22H29ClO6
Molar mass424.915
3D model (JSmol)
  • c1cc(cc(c1)Cl)OC[C@@H](/C=C/[C@H]2[C@@H](C[C@@H]([C@@H]2C/C=C\CCCC(=O)O)O)O)O
  • InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1-,11-10+/t16-,18-,19-,20+,21-/m1/s1
  • Key:VJGGHXVGBSZVMZ-QIZQQNKQSA-N

Cloprostenol is a synthetic prostaglandin analogue structurally related to prostaglandin F2-α (PGF2 α). It causes functional and morphological regression of the corpus luteum (luteolysis) in cattle.

Uses