Clobenpropit: Difference between revisions
Content deleted Content added
CAS#, etc. |
Sphilbrick (talk | contribs) replaced .png with .svg version |
||
| Line 1: | Line 1: | ||
{{chembox |
{{chembox |
||
|ImageFile=Clobenpropit. |
|ImageFile=Clobenpropit.svg |
||
|ImageSize= |
|ImageSize= |
||
|IUPACName=''N''′-[(4-chlorophenyl)methyl]-1-[3-(3''H''-imidazol-4-yl)propylthio]formamidine |
|IUPACName=''N''′-[(4-chlorophenyl)methyl]-1-[3-(3''H''-imidazol-4-yl)propylthio]formamidine |
||
Revision as of 19:29, 25 May 2009
| |
| Names | |
|---|---|
| IUPAC name
N′-[(4-chlorophenyl)methyl]-1-[3-(3H-imidazol-4-yl)propylthio]formamidine
| |
| Identifiers | |
3D model (JSmol)
|
|
PubChem CID
|
|
CompTox Dashboard (EPA)
|
|
| |
| Properties | |
| C14H17ClN4S | |
| Molar mass | 308.83 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
Clobenpropit is a histamine H3 antagonist.[1] It has neuroprotective effects via stimulation of GABA release in the brain.[2]
References
- ^ Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P (2007). "The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes". Eur. J. Pharmacol. 567 (3): 206–10. doi:10.1016/j.ejphar.2007.04.032. PMID 17537431.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Dai H, Fu Q, Shen Y, Hu W, Zhang Z, Timmerman H, Leurs R, Chen Z. The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons. European Journal of Pharmacology. 2007 Jun 1;563(1-3):117-23. PMID 17350613
.svg){kind=small} | This biochemistry article is a stub. You can help Wikipedia by expanding it. |
 | This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |