Lactase and User talk:Nick1nildram: Difference between pages

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Hi! '''[[Wikipedia:Introduction|welcome]]''' to [[Wikipedia]]!
{{Protein
|Name=Lactase
|Symbol=LCT
|AltSymbols=LAC; LPH; LPH1
|HGNCid=6530
|Chromosome=2
|Arm=q
|Band=21
|LocusSupplementaryData=
|ECnumber=3.2.1.108
|OMIM=603202
|EntrezGene=3938
|RefSeq=NM_002299
|UniProt=P09848
}}


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<!-- TEXT STARTS HERE -->
'''Lactase''' (LCT), a part of the [[β-galactosidase]] family of [[enzyme]]s, is a [[glycoside hydrolase]] involved in the [[hydrolysis]] of the [[disaccharide]] [[lactose]] into constituent [[galactose]] and [[glucose]] [[monomer]]s. In humans, lactase is present predominantly along the [[brush border]] [[Cell membrane|membrane]] of the differentiated [[enterocyte]]s lining the [[villi]] of the [[small intestine]].


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Lactase is essential for digestive hydrolysis of lactose in milk. Deficiency of the enzyme causes [[lactose intolerance]].
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The optimum [[temperature]] for lactase is about 48 °C (118.4 °F) for its activity and has an optimum [[pH]] of 6.5.


-- [[User:Utcursch|utcursch]] | [[User_talk:Utcursch|talk to me]]
==Industrial use==
[[Image:Lactase.jpg|thumb|left|400px|Reaction using lactase]]
Lactase produced commercially can be extracted both from [[yeast]]s such as ''[[Kluyveromyces fragilis]]'' and ''[[Kluyveromyces lactis]]'' and from [[fungus|fungi]], such as ''[[Aspergillus niger]]'' and ''[[Aspergillus oryzae]]''.<ref name=Seyis>Seyis I, Aksoz N. Production of lactase by ''Trichoderma sp.''. ''Food Technol Biotechnol'' 2004;42:121–124. [http://public.carnet.hr/ftbrfd/42-121.pdf Free text.] <!--Not indexed on PubMed--></ref> Its primary commercial use is to break down lactose in milk to make it suitable for people with [[lactose intolerance]]. However, the Food and Drug Administration ([[FDA]]) has not formally evaluated the effectiveness of these products.<ref>http://www.cfsan.fda.gov/~rdb/opa-g132.html</ref> Lactase is also used in the manufacture of [[ice cream]]. Because glucose and galactose are sweeter than lactose, lactase produces a more pleasant taste. Lactose also crystallises at the low temperatures of ice cream; however, its constituent products stay liquid and contribute to a smoother texture. Lactase is used in the conversion of [[whey]] into syrup.


==[[Brass Monkey]]s==
Lactase is also used to screen for blue white colonies into the MCS of various plasmid vectors in ''[[Escherichia coli]]'' or other bacteria{{Fact|date=October 2008}}.


It's bloody brass monkey weather here in Sydney tonight as a matter of fact... would you check out what I've done with that article? ... and my comments on the discussion page.
The reaction that lactase catalyzes is C12H22011 + H20 --> C6H1206 + C6H1206 + heat.


--[[User:Amandajm|Amandajm]] 11:14, 30 June 2007 (UTC)
==External links==
* ''E. coli'' β-galactosidase: {{PDB|1JYY}}
*[http://www.lsbu.ac.uk/biology/enztech/lactase.html The use of lactases in the dairy industry]
*[http://www.eurekalert.org/pub_releases/2007-02/ucl-eeu022607.php The Recent Evolution of Lactose Tolerance]
*[http://www.ebi.ac.uk/ego/DisplayGoTerm?id=GO:0000016 Gene Ontology for Lactase] helo


==Fair use rationale for Image:LDP_Waymark_Stour_Valley_Way.png==
==References==
[[Image:Ambox warning pn.svg|70px|left]]
<references/>
Thanks for uploading or contributing to [[:Image:LDP_Waymark_Stour_Valley_Way.png]]. I notice the image page specifies that the image is being used under [[Wikipedia:Fair use|fair use]] but there is no [[Wikipedia:Fair use rationale guideline|explanation or rationale]] as to why its use in Wikipedia articles constitutes fair use. In addition to the [[Wikipedia:Image copyright tags/Fair use|boilerplate fair use template]], you must also write out on the image description page a specific explanation or rationale for why using this image in each article is consistent with fair use. Suggestions on how to do so can be found [[WP:FURG|here]].


Please go to [[:Image:LDP_Waymark_Stour_Valley_Way.png|the image description page]] and edit it to include a [[Wikipedia:Fair use rationale guideline |fair use rationale]]. Using one of the templates at [[Wikipedia:Fair use rationale guideline]] is an easy way to ensure that your image is in compliance with Wikipedia policy, but remember that you must complete the template. Do not simply insert a blank template on an image page.
{{Glycoside hydrolases}}
{{Fructose and galactose metabolism}}


If you have uploaded other fair use media, consider checking that you have specified the fair use rationale on those pages too. You can find a list of 'image' pages you have edited by clicking on the "[[Special:Contributions/{{PAGENAME}}|my contributions]]" link (it is located at the very top of any Wikipedia page when you are logged in), and then selecting "Image" from the dropdown box. Note that any non-free media lacking such an explanation will be deleted one week after they have been uploaded, as described on [[Wikipedia:Criteria for speedy deletion#Images.2FMedia|criteria for speedy deletion]]. If you have any questions please ask them at the [[Wikipedia:Media copyright questions|Media copyright questions page]]. Thank you. <small>Do you want to [[Template:Bots#Message notification opt out|opt out]] of receiving this notice?</small><!-- Template:Missing rationale --> [[User:Calliopejen1|Calliopejen1]] ([[User talk:Calliopejen1|talk]]) 07:14, 12 August 2008 (UTC)
[[Category:Food additives]]
[[Category:Antiflatulents]]
[[Category:EC 3.2.1]]


==Image:LDP_Waymark_The_Monarch's_Way_on_a_Bridleway.png==
[[da:Laktase]]
I have tagged [[:Image:LDP_Waymark_The_Monarch's_Way_on_a_Bridleway.png]] as {{tl|no rationale}}, because it does not provide a [[Wikipedia:Non-free use rationale guideline|fair use rationale]]. If you believe the image to be acceptable for [[Wikipedia:Non-free content|fair use]] according to Wikipedia policy, please provide a rationale explaining as much, in accordance with the [[Wikipedia:Non-free use rationale guideline|fair use rationale guideline]], on [[:Image:LDP_Waymark_The_Monarch's_Way_on_a_Bridleway.png|the image description page]]. Some examples can be found at [[Wikipedia:Use rationale examples]]. Please also consider using {{tlp|non-free fair use in|article name}} or one of the other tags listed at [[Wikipedia:Image copyright tags/Non-free]]. Thank you. <!-- Template:Missing rationale short --> [[User:Calliopejen1|Calliopejen1]] ([[User talk:Calliopejen1|talk]]) 07:15, 12 August 2008 (UTC)
[[de:Lactase]]

[[es:Lactasa]]
==Image:LDP_Waymark_The_Monarch's_Way_on_a_Footpath.png==
[[eo:Laktazo]]
I have tagged [[:Image:LDP_Waymark_The_Monarch's_Way_on_a_Footpath.png]] as {{tl|no rationale}}, because it does not provide a [[Wikipedia:Non-free use rationale guideline|fair use rationale]]. If you believe the image to be acceptable for [[Wikipedia:Non-free content|fair use]] according to Wikipedia policy, please provide a rationale explaining as much, in accordance with the [[Wikipedia:Non-free use rationale guideline|fair use rationale guideline]], on [[:Image:LDP_Waymark_The_Monarch's_Way_on_a_Footpath.png|the image description page]]. Some examples can be found at [[Wikipedia:Use rationale examples]]. Please also consider using {{tlp|non-free fair use in|article name}} or one of the other tags listed at [[Wikipedia:Image copyright tags/Non-free]]. Thank you. <!-- Template:Missing rationale short --> [[User:Calliopejen1|Calliopejen1]] ([[User talk:Calliopejen1|talk]]) 07:15, 12 August 2008 (UTC)
[[fr:Lactase]]

[[is:Laktasi]]
== Itchen_Way_Map.png ==
[[it:Lattasi]]

[[he:לקטאז]]
Hi Nick, I've recently been trying to clarify the route of the Itchen Way on the ground, which is ambiguous on OS maps due to infrequent labelling (no indication for example that it crosses to the left bank from Abbots Worthy to Winchester!). It is clearly north of the river at the M3 underpass and east of Martyr Worthy. However (heading down stream), waymarks take it south across the river from Martyr Worthy to the Chestnut Horse at Easton, then west across the fields to Easton Lane. It presumably re-crosses the river via Easton Lane (as indicated on Explorer maps by an unnamed long distance route). This suggests your map needs a minor mod, as this loop is not shown. I have GPS data for photos taken en route if this would assist. [[User:Pterre|Pterre]] ([[User talk:Pterre|talk]]) 11:33, 11 October 2008 (UTC)
[[nl:Lactase]]
[[ja:ラクターゼ]]
[[oc:Lactasa]]
[[pl:Laktaza]]
[[pt:Lactase]]
[[fi:Laktaasi]]
[[sv:Laktas]]
[[uk:Лактаза]]
[[zh:乳糖酶]]

Revision as of 11:33, 11 October 2008

Hi! welcome to Wikipedia!

Hope you enjoy contributing to Wikipedia. Be bold in editing pages. Here are some links that you might find useful:

I hope you stick around and keep contributing to Wikipedia. Drop us a note at Wikipedia:New user log.

-- utcursch | talk to me

It's bloody brass monkey weather here in Sydney tonight as a matter of fact... would you check out what I've done with that article? ... and my comments on the discussion page.

--Amandajm 11:14, 30 June 2007 (UTC)

Fair use rationale for Image:LDP_Waymark_Stour_Valley_Way.png

Thanks for uploading or contributing to Image:LDP_Waymark_Stour_Valley_Way.png. I notice the image page specifies that the image is being used under fair use but there is no explanation or rationale as to why its use in Wikipedia articles constitutes fair use. In addition to the boilerplate fair use template, you must also write out on the image description page a specific explanation or rationale for why using this image in each article is consistent with fair use. Suggestions on how to do so can be found here.

Please go to the image description page and edit it to include a fair use rationale. Using one of the templates at Wikipedia:Fair use rationale guideline is an easy way to ensure that your image is in compliance with Wikipedia policy, but remember that you must complete the template. Do not simply insert a blank template on an image page.

If you have uploaded other fair use media, consider checking that you have specified the fair use rationale on those pages too. You can find a list of 'image' pages you have edited by clicking on the "my contributions" link (it is located at the very top of any Wikipedia page when you are logged in), and then selecting "Image" from the dropdown box. Note that any non-free media lacking such an explanation will be deleted one week after they have been uploaded, as described on criteria for speedy deletion. If you have any questions please ask them at the Media copyright questions page. Thank you. Do you want to opt out of receiving this notice? Calliopejen1 (talk) 07:14, 12 August 2008 (UTC)

Image:LDP_Waymark_The_Monarch's_Way_on_a_Bridleway.png

I have tagged Image:LDP_Waymark_The_Monarch's_Way_on_a_Bridleway.png as {{no rationale}}, because it does not provide a fair use rationale. If you believe the image to be acceptable for fair use according to Wikipedia policy, please provide a rationale explaining as much, in accordance with the fair use rationale guideline, on the image description page. Some examples can be found at Wikipedia:Use rationale examples. Please also consider using {{non-free fair use in|article name}} or one of the other tags listed at Wikipedia:Image copyright tags/Non-free. Thank you. Calliopejen1 (talk) 07:15, 12 August 2008 (UTC)

Image:LDP_Waymark_The_Monarch's_Way_on_a_Footpath.png

I have tagged Image:LDP_Waymark_The_Monarch's_Way_on_a_Footpath.png as {{no rationale}}, because it does not provide a fair use rationale. If you believe the image to be acceptable for fair use according to Wikipedia policy, please provide a rationale explaining as much, in accordance with the fair use rationale guideline, on the image description page. Some examples can be found at Wikipedia:Use rationale examples. Please also consider using {{non-free fair use in|article name}} or one of the other tags listed at Wikipedia:Image copyright tags/Non-free. Thank you. Calliopejen1 (talk) 07:15, 12 August 2008 (UTC)

Itchen_Way_Map.png

Hi Nick, I've recently been trying to clarify the route of the Itchen Way on the ground, which is ambiguous on OS maps due to infrequent labelling (no indication for example that it crosses to the left bank from Abbots Worthy to Winchester!). It is clearly north of the river at the M3 underpass and east of Martyr Worthy. However (heading down stream), waymarks take it south across the river from Martyr Worthy to the Chestnut Horse at Easton, then west across the fields to Easton Lane. It presumably re-crosses the river via Easton Lane (as indicated on Explorer maps by an unnamed long distance route). This suggests your map needs a minor mod, as this loop is not shown. I have GPS data for photos taken en route if this would assist. Pterre (talk) 11:33, 11 October 2008 (UTC)