Paraneoplastic acrokeratosis: Difference between revisions
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{{about|the cutaneous condition Bazex syndrome|the inherited condition Bazex syndrome|Bazex–Dupré–Christol syndrome}} |
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{{Infobox medical condition (new) |
{{Infobox medical condition (new) |
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| name = Paraneoplastic acrokeratosis |
| name = Paraneoplastic acrokeratosis |
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| synonyms = '''Acrokeratosis paraneoplastica of Bazex''' and '''Acrokeratosis neoplastica''')<ref name="Bolognia">{{cite book |author=Rapini, Ronald P. |author2=Bolognia, Jean L. |author3=Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |
| synonyms = '''Acrokeratosis paraneoplastica of Bazex''' and '''Acrokeratosis neoplastica''')<ref name="Bolognia">{{cite book |author=Rapini, Ronald P. |author2=Bolognia, Jean L. |author3=Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |isbn=978-1-4160-2999-1 }}</ref> |
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'''Paraneoplastic acrokeratosis''', or '''Bazex syndrome''' is a cutaneous condition characterized by psoriasiform changes of hands, feet, ears, and nose, with involvement of the nails and periungual tissues being characteristic and indistinguishable from [[psoriatic nails]]. The condition is associated with carcinomas of the upper aerodigestive tract.<ref name="Fitz2">Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. {{ISBN|0-07-138076-0}}.</ref>{{rp|665}} |
'''Paraneoplastic acrokeratosis''', or '''Bazex syndrome''' is a [[cutaneous]] condition characterized by [[wikt:psoriasiform|psoriasiform]] changes of hands, feet, ears, and nose, with involvement of the nails and [[periungual]] tissues being characteristic and indistinguishable from [[psoriatic nails]]. The condition is associated with [[carcinomas]] of the upper [[aerodigestive tract]].<ref name="Fitz2">Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. {{ISBN|0-07-138076-0}}.</ref>{{rp|665}} |
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This condition should not be confused with the other unrelated disease called Bazex syndrome, otherwise referred to as [[Bazex-Dupre-Christol syndrome]]. |
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==History== |
==History== |
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A case was first reported by [[Henri Gougerot]] and C. Grupper in 1922.<ref name=Sánchez2011>{{cite book |last1=Chiesa-Fuxench |first1=Zelma C. |last2=Ramírez |first2=Liliana |last3=Sánchez |first3=Néstor P. |editor1-last=Sánchez |editor1-first=Néstor P. |title=Atlas of Dermatology in Internal Medicine |date=2011 |publisher=Springer Science & Business Media |location=New York |isbn=978-1-4614-0687-7 |page=66 |chapter-url=https://books.google.com/books?id=PACwY7Ms2F4C&pg=PA66 |language=en |chapter=Cutaneous manifestations of internal malignancy and paraneoplastic syndromes}}</ref><ref>Gougerot, H. and Grupper, C., (1922). Dermatose érythémato-squameuse avec hyperkératose palmoplantaire, porectasies digitales et cancer de la langue latent. Paris Med, 43, pp.234-237</ref> Andre Bazex described it as a [[paraneoplastic syndrome]] in 1965.<ref name=Sánchez2011/><ref name=Bazex1980>{{cite journal |last1=Bazex |first1=A. |last2=Griffiths |first2=A. |title=Acrokeratosis paraneoplastica--a new cutaneous marker of malignancy |journal=The British Journal of Dermatology |date=September 1980 |volume=103 |issue=3 |pages=301–306 |doi=10.1111/j.1365-2133.1980.tb07248.x |pmid=7000146 |url=https://pubmed.ncbi.nlm.nih.gov/7000146/ |issn=0007-0963}}</ref> |
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This was first reported by the French Dermatologist, Andre Bazex (1911–1988), in 1945. Contrary to some publications, he did not die in 1944, as a victim of the [[Liberation of Paris|Battle for France]], but instead, was alive and well and continued his research on skin diseases up until his retirement in 1980.<ref>{{cite web | url=http://www.vgrd.org/archive/cases/2008/bazex/bazex%20abstract.htm | title=Acrokeratosis paraneoplastica in a 45-yr-old man | date=February 20, 2008 | author=Eric Ehrsam}}</ref> |
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== See also == |
== See also == |
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{{DEFAULTSORT:Acrokeratosis Paraneopastica Of Bazex}} |
{{DEFAULTSORT:Acrokeratosis Paraneopastica Of Bazex}} |
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[[Category:Conditions of the skin appendages]] |
[[Category:Conditions of the skin appendages]] |
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[[Category:Syndromes]] |
[[Category:Syndromes affecting the skin]] |
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{{skin-appendage-stub}} |
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Latest revision as of 23:45, 5 February 2024
| Paraneoplastic acrokeratosis | |
|---|---|
| Other names | Acrokeratosis paraneoplastica of Bazex and Acrokeratosis neoplastica)[1] |
| Specialty | Dermatology  |
Paraneoplastic acrokeratosis, or Bazex syndrome is a cutaneous condition characterized by psoriasiform changes of hands, feet, ears, and nose, with involvement of the nails and periungual tissues being characteristic and indistinguishable from psoriatic nails. The condition is associated with carcinomas of the upper aerodigestive tract.[2]: 665
History[edit]
A case was first reported by Henri Gougerot and C. Grupper in 1922.[3][4] Andre Bazex described it as a paraneoplastic syndrome in 1965.[3][5]
See also[edit]
- List of cutaneous conditions
- Nail anatomy
- List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer
References[edit]
- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
- ^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
- ^ a b Chiesa-Fuxench, Zelma C.; Ramírez, Liliana; Sánchez, Néstor P. (2011). "Cutaneous manifestations of internal malignancy and paraneoplastic syndromes". In Sánchez, Néstor P. (ed.). Atlas of Dermatology in Internal Medicine. New York: Springer Science & Business Media. p. 66. ISBN 978-1-4614-0687-7.
- ^ Gougerot, H. and Grupper, C., (1922). Dermatose érythémato-squameuse avec hyperkératose palmoplantaire, porectasies digitales et cancer de la langue latent. Paris Med, 43, pp.234-237
- ^ Bazex, A.; Griffiths, A. (September 1980). "Acrokeratosis paraneoplastica--a new cutaneous marker of malignancy". The British Journal of Dermatology. 103 (3): 301–306. doi:10.1111/j.1365-2133.1980.tb07248.x. ISSN 0007-0963. PMID 7000146.