Overdiagnosis bias

The overdiagnosis bias ( English length time bias ) is a falsification in medicine that can falsify the results of screening studies. In screenings , it is preferred to detect slowly progressing diseases, for example slow-growing tumors , as they have a longer symptom-free interval. Rapidly progressing diseases, on the other hand, are often discovered in the intervals between examinations based on their symptoms. For example, cancers that progress more slowly are more likely to be detected at an earlier stage through screening than cancers that progress aggressively.

As a result, the screening can falsely simulate a better treatment success, since diseases are discovered that do not have a negative impact on survival.

See also

• Lead-time bias

Individual evidence

1. ↑ Herkner, Harald, et al. "Diagnostic Studies." Successful scientific work in the clinic: Basics, interpretation and implementation: Evidence Based Medicine (2011): 197–210.
2. ^ Karl R. Aigner and Frederick O. Stephens .: Basic oncology knowledge. , P. 203
3. ↑ Lessons learned from neuroblastoma screening http://de.testingtreatments.org/tt-main-text/4-frueher-ist-nicht-zwangslaeufig-besser/lehren-aus-dem-neuroblastom-screening/
4. ↑ Length bias (English) http://www.fpnotebook.com/Prevent/Epi/LngthBs.htm
5. ^ Karl R. Aigner and Frederick O. Stephens: Onkologie Basiswissen. , P. 203

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