Argyll Robertson Sign

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Classification according to ICD-10
H57.0 Pupillary dysfunction
ICD-10 online (WHO version 2019)

The Argyll-Robertson sign occurs in cerebral disorders in the area of ​​the midbrain (tectum, four-hill plate).

Clinically, this is shown by a loss of the optical reflexes of the eye ( pupillary reflex after exposure to light), on the other hand the motor reflexes (convergence reaction and close-up reaction) are intact - so there is a reflex pupillary rigidity .

The cause is damage to the midbrain near the aqueduct , more precisely the connection between the nucleus praetectalis olivaris and the nucleus Edinger-Westphal .

The Argyll-Robertson sign typically occurs in neurosyphilis ( syphilis ), but also in other diseases (inflammation, tumor). The Scottish eye surgeon Douglas Moray Cooper Lamb Argyll Robertson , after whom the sign is named, established the link between syphilis and light rigidity of the pupils in 1869.

literature