Assembler (bioinformatics)
In bioinformatics, an assembler is a computer program that combines virtual nucleotide sequences into longer fragments by means of sequence alignments . A quantity of short DNA sequences ( reads ) obtained by shotgun sequencing is arranged in such a way that they result in the original genome .
software
AMOS ( A Modular, Open-Source Assembler ) is an open-source project that aims to create a modular and open-source assembler. The project was developed at the Institute for Genomic Research by Steven Salzberg, Mihai Pop and Art Delcher.
The Celera Assembler was developed by Gene Myers, Granger Sutton and Art Delcher at Celera from 1998 to 2002. Since then, the project has been further developed on SourceForge .
The Arachne Assembler was launched in 2000 by Serafim Batzoglou as part of his doctoral thesis. Since then it has been developed by a team led by David B. Jaffe at the Broad Institute .
A list of available assemblers can be found here: Available Assemblers .