Connective tissue nevus

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Classification according to ICD-10
D21.- Other benign neoplasms of connective and other soft tissues
ICD-10 online (WHO version 2019)

The connective tissue nevus is a circumscribed malformation ( nevus ) of the connective tissue of the skin with excessive formation of collagen and elastic fibers . If the collagen content predominates , it is called a collagenoma , if the fibers are predominantly elastic, it is called an elastome .

Synonym connective tissue nevus; english shagreen patch

The first description comes from the year 1921 by Felix Lewandowsky (quoted from C. Gutmann).

Classification

The following classification is common:

  • Nevus elasticus
  • coarse-knotted, disseminated connective tissue nevus
  • Lumbar sacral connective tissue nevus
  • Elastoma juvenile

Occurrence

Connective tissue nevi can occur in isolation or as part of syndromes such as tuberous sclerosis (Bourneville-Pringle) and Buschke-Ollendorff syndrome .

treatment

Depending on the extent and location, surgical removal or injection of steroids are possible.

literature

  • O. Lafargue, S. Fraitag, O. Boccara, F. Comoz, J. Rod, C. Turgis Mezerette, A. Dompmartin: Hamartome conjonctif étendu de l'enfant. In: Annales de dermatologie et de venereologie. Volume 144, Number 11, November 2017, pp. 700-704, doi: 10.1016 / j.annder.2017.06.006 , PMID 28760502 .
  • I. Pennacchia, H. Kutzner, DV Kazakov, T. Mentzel: Fibroblastic connective tissue nevus: Clinicopathological and immunohistochemical study of 14 cases. In: Journal of cutaneous pathology. Volume 44, number 10, October 2017, pp. 827-834, doi: 10.1111 / cup.12993 , PMID 28632950 .
  • T. Furfaro: Connective tissue nevus. In: Dermatology nursing. Volume 18, Number 2, April 2006, p. 165, PMID 16708680 .

Individual evidence

  1. ↑ a b c dermatologie / connegewebsnaevus-671 Encyclopedia Dermatology
  2. ↑ emedicine
  3. ↑ C. Gutmann: II. On the question of connective tissue nevi. In: Dermatology. 47, 2004, p. 26, doi: 10.1159 / 000251554 .
  4. ↑ N. Saki, A. Dorostkar, A. Heiran, FS Aslani: Satisfactory treatment of a large connective tissue nevus with intralesional steroid injection. In: Dermatology practical & conceptual. Volume 8, number 1, January 2018, pp. 12-14, doi: 10.5826 / dpc.0801a03 , PMID 29445568 , PMC 5808365 (free full text).