Blood-testicular barrier

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Blood-testicular barrier formed by the Sertoli cells (7) and tight junctions (8)

The blood-testis barrier is an effective barrier between the sperm precursor cells , the spermatogonia , located at the base of the testicular tubules ( tubuli seminiferi ) , and the further developed germ cells ( spermatocytes and spermatids ) located further inside the testicular tubules .

The blood-testicle barrier is formed by the Sertoli cells . They are characterized by sealing strips ( tight junctions connected). These strip-shaped connections seal the intercellular gap and thus form the blood-testicle barrier.

The blood-testicle barrier severely restricts the transport of substances from the edge to the inside of the testicular tubules and controls it. The germ cells in meiosis and the spermatogenesis are protected from harmful substances and antibodies from the body.

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