Cataplerotic reactions

Cataplerotic , also written as cataplerotic , ( ancient Greek : κατα – πλέω descend ) are reactions that mainly belong to anabolic metabolic pathways and for these take intermediates from the citric acid cycle . In contrast, there are anaplerotic reactions.

Important intermediates for such reactions are citrate (e.g. for cholesterol and fatty acid biosynthesis), succinyl-CoA (for porphyrin biosynthesis), L- malate (for gluconeogenesis ), oxaloacetate and ketoglutarate (e.g. for amino acid metabolism).

literature

• Jeremy M. Berg, John L. Tymoczko, Lubert Stryer : Biochemistry. 6 edition, Spektrum Akademischer Verlag, Heidelberg 2007. ISBN 978-3-8274-1800-5 .
• Donald Voet, Judith G. Voet: Biochemistry. 3rd edition, John Wiley & Sons, New York 2004. ISBN 0-471-19350-X .
• Bruce Alberts , Alexander Johnson, Peter Walter, Julian Lewis, Martin Raff, Keith Roberts: Molecular Biology of the Cell , 5th Edition, Taylor & Francis 2007, ISBN 978-0815341062 .