Cis effect

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Cis effect (from the Latin cis , this side ') describes an effect on gene expression through cis-acting elements , the effect of which depends on their gene location , i.e. regulatory elements on the same DNA molecule in the immediate vicinity, such as bacterial operators . In contrast to the cis effect, a trans effect occurs through the gene products of regulatory genes (these are RNA or proteins ) regardless of the gene location. The cis-effect can be divided into the effects of activators (cis-activation) and repressors (cis-repression) of gene expression.

Individual evidence

  1. ^ A b Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella, John Stirling: Oxford Dictionary of Biochemistry and Molecular Biology. Oyford University Press, Oxford, 2006, ISBN 978-0-198-52917-0 . Pp. 125, 670.
  2. James D. Watson , Amy A. Caudy, Richard M. Myers, Jan A. Witkowski: Recombinant DNA: Genes and Genomes - A Short Course . Cold Spring Harbor Press, 2007, ISBN 0-7167-2866-4 , pp. 57-58.