Trans effect

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Trans effect (from Latin trans 'beyond') refers to an effect on gene expression through the gene products of regulatory genes (these are RNA or proteins ), the effect of which is independent of their gene location . Typical examples of a trans effect are bacterial repressors . In contrast to transactivation, a cis effect takes place through cis-acting elements , i.e. regulatory elements on the same DNA molecule, such as bacterial operators . The trans effect can be divided into the effects of activators (trans-activation) and of repressors (trans-repression) of gene expression.

See also

Individual evidence

  1. ^ A b c Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella, John Stirling: Oxford Dictionary of Biochemistry and Molecular Biology. Oyford University Press, Oxford, 2006, ISBN 978-0-198-52917-0 . Pp. 125, 670.
  2. ↑ James D. Watson , Amy A. Caudy, Richard M. Myers, Jan A. Witkowski: Recombinant DNA: Genes and Genomes - A Short Course . Cold Spring Harbor Press, 2007, ISBN 0-7167-2866-4 , pp. 57-58.