Clonorchiosis

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Classification according to ICD-10
B66.1 Clonorchiasis
ICD-10 online (WHO version 2019)

The Clonorchiasis is an attack by the Chinese liver fluke disease caused. It is in East Asia ( China , Taiwan , Vietnam , Japan , Korea ) endemic . Cases in Europe are the exception and almost always introduced. The number of infected people is estimated at 20 to 30 million people.

Clinical picture

Since the leeches live in the intrahepatic biliary tract, the infestation causes epithelial growths and connective tissue remodeling in the liver parenchyma . An increase in the risk of bile duct cancer was noted. Infection with a few leeches is usually not noticed. If the infestation is pronounced (500–1000 worms), upper abdominal pain, diarrhea and fever can occur.

Diagnosis and therapy

The eggs, about 30 µm in size, can be detected in the stool. They can be easily recognized under the light microscope by their "light bulb shape".

Praziquantel and albendazole are available for treatment . The best prophylaxis is to refrain from eating raw fish, as they are part of traditional cuisine in large parts of Asia.

References

  1. H. Shin, C. Lee, H. Park, S. Seol, J. Chung, H. Choi, Y. Ahn, T. Shigemastu: Hepatitis B and C virus, Clonorchis sinensis for the risk of liver cancer: a case -control study in Pusan, Korea . In: Int J Epidemiol . tape 25 , no. 5 , 1996, pp. 933-940 , doi : 10.1093 / ije / 25.5.933 , PMID 8921477 .