Councilman corpuscles
Councilman bodies (also known as “red bodies”) are single cells in liver cells ( hepatocytes ). They are the result of liver diseases, for example acute viral hepatitis or steatohepatititis. Councilman bodies are the morphological correlate of liver cell apoptosis (controlled cell death), which can be detected as hyaline bodies.
Histologically, they are characterized by their detachment from the cell structure. Due to the complete dissolution of the cell nucleus ( karyolysis ), only the cytoplasm is left .
Eponym
Councilman bodies were named after their American discoverer, the pathologist William Thomas Councilman (1854-1933).
Individual evidence
- ↑ Xiao SY, et al .: Alteration of clinical outcome and histopathology of yellow fever virus infection in a hamster model by previous infection with heterologous flaviviruses. Am J Trop Med Hyg. 2003 Jun; 68 (6): 695-703. Full text (HTML) Full text (PDF; 965 kB) ( Page no longer available , search in web archives ) Info: The link was automatically marked as defective. Please check the link according to the instructions and then remove this notice. PMID 12887029
