DMEL

The DMELs ( English Derived Minimum Effect Level , synonym DMEL derived concentration with minimal impact) describes the exposure threshold below which there is a minimal, tolerable risk of danger to human health.

He was supported by the European Chemicals Agency in addition to from the REACH derived DNEL ( English derived no-effect level introduced concentration derived no effect). The DNEL value describes the exposure limit value below which a substance does not have any adverse effects on human health according to the state of scientific knowledge. Unlike the DNEL, the DMEL value is not anchored in the REACH regulation.

The primary goal of the REACH regulation is to replace carcinogenic , mutagenic or toxic to reproduction substances (CMR substances). In this context, REACH does not provide any limit values for substances for which DNEL values cannot be determined.

The acceptable cancer risk concealed in the DMEL value is not a quantity that can be scientifically derived, but should be the expression of a social consensus . The concept that the registrant (manufacturer or importer) has to decide what is an acceptable cancer risk is criticized . As a result, the majority of registrations for carcinogenic substances have DNELs.

Individual evidence

↑ ^a ^b DIN EN 689: 2016-07 (draft) exposure at the workplace; Measurement of exposure through inhalation of chemical agents; Strategy for checking compliance with occupational exposure limits; German and English version prEN 689: 2016 (Workplace exposure; Measurement of exposure by inhalation to chemical agents; Strategy for testing compliance with occupational exposure limit values; German and English version prEN 689: 2016). Beuth Verlag, Berlin, p. 24.
↑ ^a ^b ^c Bernhard Brandt: Application of limit values and other assessment criteria for hazardous substances in the workplace - European and national regulations, procedures in practice. In: Hazardous substances - cleanliness. Air . 77, No. 3, 2017, ISSN 0949-8036 , pp. 54-58.
↑ Michael Au, Reinhold Rühl: Expectations of occupational health and safety on REACH. In: Hazardous substances - cleanliness. Air. 68, No. 4, 2008, ISSN 0949-8036 , pp. 111-117.
↑ ^a ^b ^c Joe Püringer: DMEL values as limit values for carcinogens - a problematic concept in the slipstream of REACH. In: Hazardous substances - cleanliness. Air. 70, No. 5, 2010, ISSN 0949-8036 , pp. 175-182.
↑ Joe Püringer: "Derived Minimal Effect Levels" (DMEL): Deficits one year after the REACH registration requirement. In: Hazardous substances - cleanliness. Air. 71, No. 11/12, 2011, ISSN 0949-8036 , pp. 471-480.
^ ^A ^b Corinne Ziegler: Munich Dangerous Substance Days: Criticism of DMEL. In: Hazardous substances - cleanliness. Air. 72, No. 1/2, 2012, ISSN 0949-8036 , pp. 34-37.

[q0-1] DIN EN 689: 2016-07 (draft) exposure at the workplace; Measurement of exposure through inhalation of chemical agents; Strategy for checking compliance with occupational exposure limits; German and English version prEN 689: 2016 (Workplace exposure; Measurement of exposure by inhalation to chemical agents; Strategy for testing compliance with occupational exposure limit values; German and English version prEN 689: 2016). Beuth Verlag, Berlin, p. 24.

[q1-2] Bernhard Brandt: Application of limit values and other assessment criteria for hazardous substances in the workplace - European and national regulations, procedures in practice. In: Hazardous substances - cleanliness. Air . 77, No. 3, 2017, ISSN 0949-8036 , pp. 54-58.

[3] Michael Au, Reinhold Rühl: Expectations of occupational health and safety on REACH. In: Hazardous substances - cleanliness. Air. 68, No. 4, 2008, ISSN 0949-8036 , pp. 111-117.

[q2-4] Joe Püringer: DMEL values as limit values for carcinogens - a problematic concept in the slipstream of REACH. In: Hazardous substances - cleanliness. Air. 70, No. 5, 2010, ISSN 0949-8036 , pp. 175-182.

[5] Joe Püringer: "Derived Minimal Effect Levels" (DMEL): Deficits one year after the REACH registration requirement. In: Hazardous substances - cleanliness. Air. 71, No. 11/12, 2011, ISSN 0949-8036 , pp. 471-480.

[q3-6] A ^b Corinne Ziegler: Munich Dangerous Substance Days: Criticism of DMEL. In: Hazardous substances - cleanliness. Air. 72, No. 1/2, 2012, ISSN 0949-8036 , pp. 34-37.