Degradosome
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The degradosome is a bacterial protein complex that is involved in the breakdown of mRNA . The complex consists of the endoribonuclease RNase E , the phosphate-dependent exoribonuclease polynucleotide phosphorylase (PNPase) and the DEAD-box RNA helicase B (RhlB). The composition of the degradosome varies depending on the organism. Similar protein complexes, called exosomes and made up of up to ten proteins, are known in eukaryotes and archaa .
Individual evidence
- ↑ Elena Evguenieva-Hackenberg (2005): RNA-degrading protein complexes. In: Biospectrum. 11: 526-527. PDF
literature
- Carpousis, AJ (2007): The RNA degradosome of Escherichia coli: an mRNA-degrading machine assembled on RNase E. In: Annu. Rev. Microbiol. 61: 71-87. PMID 17447862 doi : 10.1146 / annurev.micro.61.080706.093440