Diphallia

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Classification according to ICD-10
Q55.6 Other congenital malformations of the male genital organs
ICD-10 online (WHO version 2019)

Diphallia (from the Greek δι- di- "double" and φαλλός phallós "penis") is a very rare genital malformation with double formation of the penis . It occurs only once in around 5.5 million newborns in humans. About 100 cases have been described in the literature so far. The first case dates back to 1609 in Bologna. So far there is no information about the frequency in other mammals. The formation of a diphallus is not to be confused with the physiologically paired hemipenis of the scallops .

Due to the very low incidence based explanations for the development of this Embryopathie largely on guesswork: Between 23 and 25 days of pregnancy separates the embryo in the back of the mesoderm of the genital eminence of the urogenital sinus and rectum to mold around the penis. Influences damaging the fetus during this phase, which lead to malfunctions in the area of ​​the Homeobox genes , could hinder the fusion of the paired structures of the penis.

Usually one of the two penises is stronger than the other. The doubling can extend over the entire length of the penis (Diphallus bifidus) or it can be limited to the area of ​​the glans (Diphallus glandularis). Diphallia is often associated with other malformations of the urogenital tract and the rectum, for example hypospadias and splitting of the scrotum . The penises can be next to or on top of each other, close together or at some distance from each other. Urine can be passed through either or both. Those affected are mostly sterile .

See also

Individual evidence

  1. ^ PM Tirtayasa, RB Prasetyo, A. Rodjani: Diphallia with associated anomalies: a case report and literature review. In: Case reports in urology. Volume 2013, 2013, p. 192960, ISSN  2090-696X . doi: 10.1155 / 2013/192960 . PMID 24383036 . PMC 3870645 (free full text).
  2. S. Acimi: diphallia Complete. In: Scandinavian journal of urology and nephrology. Volume 38, Number 5, 2004, pp. 446-447, ISSN  0036-5599 . doi: 10.1080 / 00365590310019981 . PMID 15764263 .
  3. ^ R. Chadha et al .: Complete diphallia associated with features of covered exstrophy. In: J Pediatr Surg. , 2001 Jul, 36 (7): E12, PMID 11431797
  4. Hoffmann-LaRoche-AG (Ed.): Roche Lexicon Medicine. 4th revised and expanded edition. Urban & Schwarzenberg, Munich a. a. 1998, ISBN 3-541-11214-X .