Dyshemoglobin

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As dyshemoglobins refers to derivatives of hemoglobin , the red blood pigment in red blood cells that are not available for the oxygen transport.

The most common dyshemoglobins are carboxyhemoglobin (COHb, norm ≤ 0.8-1.0 %, in smokers up to 5%, max. 10%), methemoglobin (MetHb, norm ≤ 0.5-1.0%), which are rarer types Sulfhemoglobin as well as carboxysulfhemoglobin. The presence of dyshemoglobins affects the ability of the blood to carry oxygen and can lead to hypoxemia . The concentration of dyshemoglobins in the blood is measured with hemoximeters or devices for blood gas analysis . Dyshemoglobins such as COHb or MetHb change the color of the blood and can therefore affect the accuracy of pulse oximeters .

literature

  • Michael Fresenius, Michael Heck: Anesthesiology revision course. Preparation for the anesthesiological specialist examination and the European diploma . 5th, completely updated edition. Springer, Berlin / Heidelberg / New York, NY 2007, ISBN 978-3-540-46575-1 , doi : 10.1007 / 978-3-662-09752-6 .

Individual evidence

  1. ^ Rolf Rossaint, Christian Werner, Bernhard Zwißler: Die Anästhesiologie. General and special anesthesiology, pain therapy and intensive care medicine . 3rd completely updated and expanded edition. Springer-Verlag, Berlin / New York 2012, ISBN 978-3-642-21125-6 , pp. 143 ( books.google.de ).
  2. Norbert Roewer, Holger Thiel, Christian Wunder: Anesthesia compact. Clinical Practice Guide . 4th edition. Georg Thieme Verlag, Stuttgart 2012, ISBN 978-3-13-158284-3 , p. 57 ( books.google.de ).
  3. SP Holbrook, A. Quinn: An unusual explanation for low oxygen saturation . In: British Journal of Anesthesia . tape 101 , no. 3 , June 18, 2008, p. 350-353 , doi : 10.1093 / bja / aen183 , PMID 18567676 .