Electrochemiluminescence

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The electrochemiluminescence (ECL) is a process by which highly reactive substances are generated from stable precursors by applying a voltage to the surface of an electrode. These substances react with each other and emit light. Compared to other chemiluminescence reactions, the light in the ECL is not generated chemically, but electrically.

Electrochemiluminescence occurs with a large number of radioactive and non-radioactive substances, such as ruthenium . The development of ECL immunassays is based on the use of a ruthenium complex and tripropylamine (TPA). The immunological complexes such as the ruthenium complex are bound to streptavidin- coated microparticles and placed under tension.

See also

Individual evidence

  1. Axel M. Gressner, Torsten Arndt (Ed.): Lexicon of the Medical Laboratory Diagnostics . 2nd Edition. Springer, Berlin, Heidelberg 2013, ISBN 978-3-642-12921-6 , pp. 433 .