Epimerases

The epimerases are enzymes and belong to the subgroup of isomerases . Epimers often play a role in the structural transformation of organic molecules . Epimers are molecules that differ only in the asymmetric arrangement of the substituents on a carbon atom. Epimerases are thus enzymes that can change the three-dimensional arrangement of the four different substituents on this carbon atom (= stereocenter ).

Examples

UDP-galactose ↔ UDP glucose (enzyme: UDP-glucose-4-epimerase)

Web links

Epimerase (medical dictionary)

Individual evidence

↑ Tanner, ME .: Understanding nature's strategies for enzyme-catalyzed racemization and epimerization . In: Acc. Chem. Res . 35, No. 4, 2002, pp. 237-246. doi : 10.1021 / ar000056y . PMID 11955052 .
^ Albert Gossauer: Structure and reactivity of biomolecules , Verlag Helvetica Chimica Acta, Zurich, 2006, p. 450, ISBN 978-3-906390-29-1 .

[1] Tanner, ME .: Understanding nature's strategies for enzyme-catalyzed racemization and epimerization . In: Acc. Chem. Res . 35, No. 4, 2002, pp. 237-246. doi : 10.1021 / ar000056y . PMID 11955052 .

[Gossauer-2] Albert Gossauer: Structure and reactivity of biomolecules , Verlag Helvetica Chimica Acta, Zurich, 2006, p. 450, ISBN 978-3-906390-29-1 .