Fowler-Christmas-Chapple Syndrome

Classification according to ICD-10
R39.1	Other micturition disorders
ICD-10 online (WHO version 2019)

The Fowler-Christmas-Chapple syndrome , English as Fowler's Syndrome called, is a bladder dysfunction in young women due to a malfunction of the bladder sphincter and occurs more frequently associated with polycystic ovary syndrome on.

Not to be confused is Fowler's syndrome , which describes a congenital disease with a vascular change affecting the brain (zebrebral vasculopathy ) and, as a result, tissue destruction with hydrocephaly or (hydro) anencephaly .

The name refers to the first author of the first description from 1985 by the British doctor Clare J. Fowler .

distribution

The frequency is given as less than 1 in 1,000,000. On the other hand, it is said to be the most common cause of urinary retention .

clinic

Clinical features are:

Urinary retention
Residual urine
Abnormal muscle activity on the electromyogram
No apparent anatomical abnormality or neurological disorder

When complications can urinary tract infections occur.

treatment

Sacral neurostimulation or sacral neuromodulation can be used as therapy .

literature

CJ Fowler, RS Kirby, MJ Harrison: Decelerating burst and complex repetitive discharges in the striated muscle of the urethral sphincter, associated with urinary retention in women. In: Journal of Neurology, Neurosurgery, and Psychiatry . Vol. 48, No. 10, October 1985, pp. 1004-1009, PMID 4056803 , PMC 1028539 (free full text).
CJ Fowler, TJ Christmas, CR Chapple, HF Parkhouse, RS Kirby, HS Jacobs: Abnormal electromyographic activity of the urethral sphincter, voiding dysfunction, and polycystic ovaries: a new syndrome? In: BMJ (Clinical research ed.). Vol. 297, No. 6661, December 1988, pp. 1436-1438, PMID 3147005 , PMC 1835186 (free full text).

Web links

Right diagnosis

Individual evidence

^ Rare Diseases
↑ ^a ^b ^c Fowler-Christmas-Chapple syndrome. In: Orphanet (Rare Disease Database).
^ Fowler syndrome. In: Orphanet (Rare Disease Database).
↑ CJ Fowler, RS Kirby: Abnormal electromyographic activity (decelerating burst and complex repetitive discharges) in the striated muscle of the urethral sphincter in 5 women with persisting urinary retention. In: British Journal of Urology . Vol. 57, 1985, pp. 67-70.
↑ ^a ^b Fowler's syndrome

[1] Rare Diseases

[Orpha-2] Fowler-Christmas-Chapple syndrome. In: Orphanet (Rare Disease Database).

[3] Fowler syndrome. In: Orphanet (Rare Disease Database).

[4] CJ Fowler, RS Kirby: Abnormal electromyographic activity (decelerating burst and complex repetitive discharges) in the striated muscle of the urethral sphincter in 5 women with persisting urinary retention. In: British Journal of Urology . Vol. 57, 1985, pp. 67-70.

[FS-5] Fowler's syndrome