Francis Osborne
Francis Osborne is the name of the following people:
- Francis Osborne (theologian) (1593–1659), English Puritan theologian
- Francis Osborne, 5th Duke of Leeds (1751–1799), British politician
- Francis Osborne, 12th Duke of Leeds (1884–1964), British aristocrat and diplomat
- Francis D'Arcy-Osborne, 7th Duke of Leeds (1798-1859), British aristocrat