Paired Associative Stimulation

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The paired associative stimulation ( engl. : Paired Associative Stimulation , PAS ) provides a method to study the functional ability reorganization represents the nervous system.

Basics

In paired associative stimulation, electrically induced stimulation of a peripheral nerve is paired with synchronous transcranial magnetic stimulation over the motor cortex . As a result of the paired associative stimulation, mainly cortical adaptation phenomena result, which are expressed in a persistent change in synaptic interactions.

Individual evidence

  1. ↑ E. Castel-Lacanal, P. Marque, J. Tardy, X. Boissezon, V. Guiraud, F. Chollet, I. Loubinoux, M. Simonetta-Maureau: Induction of cortical plastic changes in wrist Muscles by paired associative stimulation the recovery phase of stroke patients. In: Neurorehabilitation and Neural Repair. 23, 2009, pp. 366-372.
  2. ^ R. Huber, S. Määttä, SK Esser, S. Sarasso, F. Ferrarelli, A. Watson, F. Ferreri, MJ Peterson, G. Tononi: Measures of Cortical Plasticity after Transcranial Paired associative stimulation predict changes in electroencephalogram slow- wave activity during subsequent sleep. In: Journal of Neuroscience. 28, 2008, pp. 7911-7918.
  3. ↑ S. Meunier, H. Russ, M. Simonetta-Moreau, M. Hallett: Changes in spinal excitability after PAS. In: Journal of Neurophysiology. 97, 2007, pp. 3131-3135.
  4. ↑ K. Stefan, E. Kunesch, R. Benecke, LG Cohen, J. Classen: Mechanisms of enhancement of human motor cortex excitability induced by interventional paired associative stimulation. In: Journal of Physiology. 543, 2002, pp. 699-708.
  5. ↑ K. Stefan, E. Kunesch, LG Cohen, R. Benecke, J. Classen: Induction of plasticity in the human motor cortex by paired associative stimulation. In: Brain. 123, 2000, pp. 572-584.

See also