Gradenigo Syndrome

Computed tomography of petrositis. Gas (black spots) can be seen as a complication in the adjacent interior of the skull

Classification according to ICD-10
H66.0	Acute purulent otitis media
ICD-10 online (WHO version 2019)

The Gradenigo syndrome (Syn. Lannois-Gradenigo syndrome , pyramidal tip syndrome , English Gradenigo's triad ) is the result of an infectious inflammation of the cells of the temporal pyramid ( petrositis ). The syndrome is a rare complication of acute otitis media . If the inflammation spreads into the interior of the skull, it causes damage to the neighboring cranial nerves through collateral edema or inflammatory infiltration with the following symptoms (Gradenigo triad):

• Severe pain behind the eye and face, the supply area of ​​the trigeminal nerve (cranial nerve)
• Double vision caused by paralysis of the eye muscles, which are supplied by the oculomotor nerve (III. Cranial nerve) and the abducens nerve (VI. Cranial nerve)
• Otitis media with purulent discharge from the ear

The Italian ear specialist Giuseppe Conte Gradenigo (1859–1926) first described the disease in 1904 .

See also

• Paratrigeminal Syndrome
• Tolosa Hunt Syndrome

Individual evidence

1. ↑ Alphabetical directory for the ICD-10-WHO Version 2019, Volume 3. German Institute for Medical Documentation and Information (DIMDI), Cologne, 2019, p. 334

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !