Hoigné syndrome

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The Hoigné syndrome refers to a reversible, not requiring treatment symptoms after intramuscular administration of depot penicillins . According to current observations, however, Hoigné syndrome can also be triggered by other drugs such as lidocaine .

It is possibly caused by accidental intravenous administration and the resulting microembolic events in the brain and lungs or by the penetration of penicillin crystals into previously damaged veins .

The patients report visual and acoustic sensations (noises, veiled vision, figure vision, etc.), confusion, restlessness and fear of death. Normally no circulatory events occur. The duration of these symptoms is usually limited to a few minutes (15–20 min).

These symptoms were first described by the Swiss doctor Rolf Hoigné in 1959.

literature

  • W. Schreiber, JC Krieg: The Hoigné Syndrome. Case history and current literature overview. In: The neurologist. 2001; (72), pp. 546-548. PMID 11478227