In-transit metastasis
As in-transit metastases (locoregional skin metastases) is referred to in the oncology regionäre tumor metastases ( metastases ) at skin cancers , the cm at a distance of more than 2 from the primary tumor (primarius) have formed removed and in the draining lymph located.
Pathogenesis
It is assumed that the in-transit metastases are formed by tumor cells “getting caught” in the small lymph vessels. The cancer cells thus fixed in the lymph vessels then begin to proliferate .
Delimitations
So-called local recurrences must be distinguished from in-transit metastases . These are remnants of an incompletely removed tumor that was able to develop further.
If the regional metastases are less than 2 cm from the original primary tumor, they are called satellite metastases . This terminology is arbitrary and has its origin in the safety margins around the primary tumor. However, this distinction has proven to be irrelevant for the prognosis.
If the metastases are in the lymph nodes, one speaks of lymph node metastases .
Individual evidence
- ↑ Peter Fritsch: Dermatology Venerology. 2nd edition, Springer, 1983, ISBN 3-540-00332-0 , p. 639. Restricted preview in the Google book search
- ↑ a b L. Kretschmer: metastasis surgery. In: Rolf-Markus Szeimies, Axel Hauschild, among others (ed.): Tumors of the skin. Georg Thieme Verlag, 2009, ISBN 3-131-58681-8 , p. 360. Restricted preview in the Google book search